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This medication is utilized to take care of depression. Additionally it is used with other therapies for the treatment of nighttime bed-wetting (enuresis) in kiddies. Using this medicine to treat despair may boost your mood, sleep, appetite, and degree of energy and might help restore your interest in day-to-day living. Imipramine can help your son or daughter control nighttime bed-wetting.

Imipramine belongs to a class of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain natural substances (neurotransmitters such as for instance norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a specific natural substance (acetylcholine) on the bladder.

OTHER USES: This section contains uses of this drug that are not detailed in the approved professional labeling for the drug but that could be prescribed by your wellbeing care professional. Use this drug for a disorder that is listed in this section only if it has been so prescribed by the wellness care expert.

This drug may also be used for the treatment of anxiety and panic disorders.

Exactly how to use Tofranil

Read the medicine Guide available from your pharmacist. Consult your doctor or pharmacist for those who have any questions.

Take this medication by lips with or without food, frequently 1-4 times daily or as directed by your physician. If you have daytime drowsiness, your doctor may direct you to take the entire dose once daily at bedtime. Dosage is based on your condition that is medical and to therapy. In children, dosage may be based on also body weight. To reduce your risk of adverse effects, your doctor may start you at a dose that is low gradually raise your dose.

When found in children for bed-wetting, imipramine ought to be taken one hour before bedtime. The drug may be given earlier in separate doses (e.g., one dose in the afternoon and one dose at bedtime) if your child usually wets the bed early in the night.

Follow your physician's instructions carefully. Do not take more or less medication or frequently take it more than prescribed. Your condition will maybe not improve any faster along with your threat of side results will increase. Use this medication regularly so that you can obtain the most benefit from it. To help you remember, use it at the time( that is same) each time.

This medication does not work right away. It may take up to 3 weeks if you are taking this medication for depression before you experience the full benefits.

It is important to carry on using this medication regardless if you feel great. Never abruptly stop taking this medication without consulting your doctor. Some conditions may be worse if the drug is abruptly stopped. Your dose may need to be gradually reduced.

When used for an excessive period in kids for bed-wetting, this medication may not work as well and may also require dosing that is different. Talk with the physician if this medicine stops working well.

Inform your physician if your condition persists or worsens.

Side Effects

Dry lips, blurred vision, headache, drowsiness, dizziness, constipation, nausea, vomiting, loss of appetite, diarrhea, stomach cramps, weight gain/loss, and increased sweating might occur. If any of these effects persist or worsen, notify your pharmacist or doctor immediately.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your physician immediately if some of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unusual breast milk production, irregular/painful menstrual periods, muscle stiffness, restlessness, ringing in the ears, sexual dilemmas (e.g., decreased sexual ability, alterations in desire), shakiness (tremors), numbness/tingling of the hands/feet, pain/redness/swelling of hands or feet, trouble urinating.

Tell your doctor right away if any among these uncommon but extremely adverse that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and rarely cause a tremendously serious condition called serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help appropriate away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, serious dizziness, serious nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Get help that is medical away when you yourself have any very severe part results, including: upper body discomfort, slow/fast/irregular heartbeat, fainting, seizures, slurred message, weakness on one part of the human anatomy, attention pain/swelling/redness, eyesight changes (such as for example seeing rainbows around lights at night).

An extremely serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

It is not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Call your medical professional for medical advice about negative effects. You may report side effects to Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about part results. You'll report effects that are side Health Canada at 1-866-234-2345.


Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (such as desipramine, amitriptyline); or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Communicate with your pharmacist for lots more details.

This medication must not be used if you have got a specific condition that is medical. Before using this medicine, consult your doctor or pharmacist if you have had: a heart attack that is recent.

Before using this medicine, tell your doctor or pharmacist your health background, particularly of: breathing problems (e.g., asthma, chronic bronchitis), individual or genealogy of glaucoma (angle-closure type), diabetes, eating disorders (e.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease), liver issues, kidney problems, personal or genealogy of other mental/mood conditions (e.g., manic depression, schizophrenia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (age.g., due to enlarged prostate), any condition that may boost your risk of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, brain injury/disease including stroke), specific types of tumors (e.g., pheochromocytoma, neuroblastoma).

Imipramine may cause a condition that affects the center rhythm (QT prolongation). QT prolongation can seldom cause serious (rarely fatal) fast/irregular heartbeat as well as other symptoms (such as serious dizziness, fainting) that require medical attention right away.

The risk of QT prolongation may be increased when you yourself have certain conditions that are medical are taking other drugs that will cause QT prolongation. Before making use of imipramine, inform your doctor or pharmacist of most the drugs you are taking and if you have some of the following conditions: certain heart problems (heart failure, sluggish heartbeat, QT prolongation in the EKG), genealogy of specific heart problems (QT prolongation in the EKG, unexpected cardiac death).

Minimal levels of potassium or magnesium into the blood may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your doctor about using imipramine properly.

Before having surgery, tell your doctor or dentist that you will be taking this medicine.

This drug could make you dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit alcoholic beverages.

To decrease dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

This drug may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Check your blood sugar regularly as directed by your doctor. Tell your doctor right away if you have symptoms such as increased thirst/urination, shakiness, unusual sweating, or hunger. Your anti-diabetic medication or diet may prefer to be adjusted.

Older grownups may become more sensitive to the side effects of this drug, especially dizziness (more likely whenever standing up), drowsiness, constipation, trouble urinating, mental/mood changes (such as confusion, agitation) and heart results such as QT prolongation (see above). Dizziness, drowsiness, and confusion can raise the danger of falling.

Care is preferred when using this medication in children. (See also the Warning section.)

This medication is used only when obviously needed during pregnancy. Infants created to mothers who took comparable medications during pregnancy may have signs such as trouble urinating, prolonged sleepiness, shaking, and seizures. Talk about the risks and benefits with your doctor.

Since untreated mental/mood issues (such as depression, anxiety, anxiety attacks) can be a condition that is serious do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your physician before breast-feeding.

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