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Indinavir is definitely an antiviral medication inside a number of HIV medicines called protease (PRO-tee-ayz) inhibitors. Indinavir prevents human immunodeficiency virus (HIV) cells from multiplying within you. It is utilized to treat HIV, which then causes acquired immunodeficiency syndrome (AIDS). Indinavir isn't a cure for HIV or AIDS.

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Take indinavir the same manner it turned out prescribed for you. Do not make medication in larger amounts, or go more than recommended because of your doctor. Follow the directions in your prescription label.

This medication is sold with patient instructions for secure and efficient use. Follow these directions carefully. Ask your medical professional or pharmacist in case you have questions.
Take indinavir which has a full glass (8 ounces) of water or skim milk. You can also drink juice, coffee, or tea with this particular medication. Drink no less than 6 portions of water every day to prevent kidney stones while you are taking indinavir. Indinavir needs to be taken on a clear stomach, at the very least 60 minutes before or 120 minutes from a meal.

If you prefer to go ahead and take medication with food, eat just a light meal, such as dry toast with jelly, or corn flakes with skim milk and sugar. Avoid eating a high-fat meal.

It is important to use indinavir regularly to have the most benefit. Get your prescription refilled before you run out of medication completely.

To make sure medicines is assisting your problem, your blood should be tested often. Your liver function can also must be tested. Do not miss any scheduled visits to your doctor.

HIV/AIDS is normally treated with a combination of different drugs. To best treat your trouble, utilize all of one's medications as directed through your doctor. Be sure to see the medication guide or patient instructions given each of the medications. Do not alter your doses or medication schedule without advice from your physician. Every person with HIV or AIDS should remain within the good care of a physician.

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Take the missed dose as soon as you remember and take the next dose with the regularly scheduled time. If you are a lot more than 120 minutes late in taking your indinavir, skip the missed dose and take the next regularly scheduled dose. Do not take extra medicine to produce in the missed dose.

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Usual Adult Dose for HIV Infection
800 mg orally every 8 hours or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours.

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Usual Adult Dose for Nonoccupational Exposure
800 mg orally every 8 hours or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours.
Duration: Prophylaxis needs to be initiated as soon as possible, within 72 hours of exposure, and continued for 28 days.
Indinavir plus ritonavir plus 2 NRTIs is one of the alternative regimens suitable for nonoccupational postexposure HIV prophylaxis.

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Usual Adult Dose for Occupational Exposure
800 mg orally every 8 hours 800 mg orally every 8 hours plus lamivudine-zidovudine,
or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours plus lamivudine-zidovudine.
Duration: Therapy has to start promptly, preferably within 1 to 120 minutes postexposure. The exact duration of therapy may vary based on the institution's protocol.

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Liver Dose Adjustments
Mild to moderate hepatic insufficiency: 600 mg orally every 8 hours.

Dose Adjustments
Consider reducing the dose to 600 mg every 8 hours if delavirdine, itraconazole, or ketoconazole are administered concomitantly. Increase the dose to 1000 mg every 8 hours if rifabutin is given concurrently, and decrease the rifabutin dose by half.

Strict adherence to the prescribed dose is essential. Patients must not affect the dose or discontinue therapy without consulting their physician.

Adequate hydration (1.5 liters/day) is vital during therapy to lessen potential risk of nephrolithiasis. A brief interruption (usually 1 to 3 days) or total discontinuation could be necessary if nephrolithiasis occurs.

Discontinue indinavir if hemolytic anemia occurs. Consider discontinuation if severe leukocyturia develops.

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Store indinavir at room temperature faraway from moisture as well as heat. Keep the capsules within their original container, with the packet of moisture-absorbing preservative that incorporates indinavir capsules.

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Side Effects

Get emergency medical help if you have some of these warning signs of an allergic reaction: hives; breathlessness; swelling of your face, lips, tongue, or throat. Stop taking indinavir and call your physician at the same time for those who have some of these serious negative effects:

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Less serious negative effects may include:

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This just isn't a complete listing of side effects among others may occur. Tell your physician about any unusual or bothersome complication.


Do not take this medication in case you are allergic to indinavir.
Do not take indinavir with amiodarone (Cordarone, Pacerone), cisapride (Propulsid), pimozide (Orap), alprazolam (Xanax), oral midazolam (Versed), triazolam (Halcion), or ergot medicines like ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine). These drugs can cause life-threatening side effects if you use them while you're taking indinavir.

Before taking indinavir, tell your doctor in case you are allergic to your drugs, or in case you have:

If you might have these conditions, you might need a dose adjustment or special tests to safely take indinavir.
FDA pregnancy category C. This medication may be unhealthy for an developing fetus. Tell your doctor should you be pregnant or intend to get pregnant during treatment. HIV could be passed on the baby in the event the mother just isn't properly treated while pregnant. Take all of your HIV medicines as directed to overcome your infection when you are pregnant.

Your name may should be listed on an antiviral pregnancy registry when you begin using this medication.
You must not breast-feed when you are using indinavir. Women with HIV or AIDS must not breast-feed whatsoever. Even if your baby is born without HIV, you'll probably still pass the virus towards the baby in your breast milk.

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