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Uses

INDICATIONS

Micronase (Glyburide) is definitely an oral diabetes medicine that helps control blood glucose levels.

Glyburide is employed to deal with diabetes.

This medication is not for treating type 1 diabetes.

Glyburide could also be used for other purposes unpublished within this medication guide.

INSTRUCTIONS

Take the same manner prescribed because of your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions on your own prescription label. Your doctor may occasionally alter your dose to make sure you obtain the best results.

Take glyburide using your first meal for the day, unless your medical professional informs you otherwise.

Your blood glucose levels should be checked often, and you'll need other blood tests at your medical professional's office. Visit a medical expert regularly.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar available in case you have symptoms of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and should not eat or drink, work with an injection of glucagon. Your doctor can provide a prescription for the glucagon emergency injection kit and show you the way to provide the injection.

Also look for signs of blood glucose which is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and weight loss.

Check your blood sugar carefully during a duration of stress or illness, in the event you travel, exercise more than usual, drink alcohol, or skip meals. These things may affect your blood sugar levels plus your dose needs might also change.

Your doctor might prefer you to stop taking glyburide for a short period of time in case you become ill, use a fever or infection, or if you have surgical procedures or a medical emergency.
Ask your physician how you can adjust your glyburide dose if needed. Do not improve your medication dose or schedule without your medical professional's advice.

If you'll find any modifications in the manufacturer, strength, or type of glyburide you use, your dosage needs may change. Always check your refills to ensure that you have received the proper brand and sort of medicine prescribed from your doctor.

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DOSAGE

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Take as prescribed through your doctor.

STORAGE

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Store at room temperature, shielded from moisture, heat, and light.

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Active ingredient: Glyburide

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Side Effects

Stop using glyburide and have emergency medical help if you've got all of these warning signs of a hypersensitivity: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call a medical expert immediately if you have these serious unwanted side effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots through your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted effects can include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete list of unwanted effects among others may occur. Call your physician for health advice about negative effects.

Precautions

You should avoid using this medication in case you are allergic to glyburide, or:

if you are undergoing treatment with bosentan (Tracleer);

if you've type 1 diabetes; or

in the event you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

To make sure you can safely take glyburide, tell a medical expert if you might have some of these other difficulties:

hemolytic anemia (too little red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

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liver or kidney disease;

should you are allergic to sulfa drugs; or

if you have been using insulin or taking chlorpropamide (Diabinese).

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Certain oral diabetes medications may improve your chance of serious heart problems. However, not handling your diabetes may damage your heart and also other organs. Talk to your doctor concerning the risks and benefits of treating your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication at the time of delivery. Tell your physician should you are pregnant or prefer to conceive while using the medicines. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.

Do not use this medication without telling your medical professional in the event you are breast-feeding an infant. Older adults might be more prone to have low blood glucose levels while taking glyburide.

 

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Important safety information:

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You must avoid using prescription drugs if you are allergic to glyburide, if you are receiving care with bosentan (Tracleer), if you have type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Before taking glyburide, tell your physician if you are allergic to sulfa drugs, if you might have been using insulin or chlorpropamide (Diabinese), or if you've got hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care never to let your blood glucose levels get too low. Low blood sugar levels (hypoglycemia) can occur should you skip lunch, exercise to much time, consume alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you might have low blood sugar levels. Other sugar sources include orange juice and milk. Be sure your loved ones and pals know the best way to assist you in an unexpected emergency.

Drug interactions

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Tell your physician about other medications you use, especially:

a blood thinner including warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor for example enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), among others; or

an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), and others.

Using certain medicines can make it tougher for one to tell when you might have low blood sugar levels. Tell a medical expert in the event you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers including atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), among others.

You might be more likely to have hyperglycemia (high blood sugar) in the event you take glyburide with:

isoniazid;

diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine among others);

thyroid medicine (Synthroid yet others);

birth control pills along with other hormones;

heart or blood pressure medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, among others);

seizure medicines (Dilantin while others); and

diet pills or medicines to treat asthma, colds or allergies.


You may be very likely to have hypoglycemia (low blood sugar levels) in case you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or hypertension medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, among others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are not complete and you can find many other medicines that may increase or decrease the effects of glyburide on reducing your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling your doctor.

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