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Precautions

Do NOT use Fluoxetine if:

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• you might be allergic to your ingredient in Fluoxetine

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• you consider or took a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days

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• you take a fenfluramine derivative (eg, dexfenfluramine), an H₁ antagonist (eg, astemizole, terfenadine), nefazodone, pimozide, a serotonin-norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, paroxetine), sibutramine, thioridazine, or tryptophan.

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Contact your medical professional or doctor without delay if all of these connect with you.

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Some medical ailments may connect to Fluoxetine. Tell a medical expert or pharmacist in case you have any medical conditions, particularly when any from the following affect you:

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• if you are pregnant, about to conceive, or are breast-feeding

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• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• when you have allergies to medicines, foods, or other substances

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• if you or a family member features a reputation bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse

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• for those who have a history of seizures, heart problems, liver problems, severe kidney problems, stomach or bowel bleeding, diabetes, or metabolism problems

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• if you might be dehydrated, have low blood sodium levels, or are drinking alcoholic beverages

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• if you'll be having electroconvulsive therapy (ECT).

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Some medicines may communicate with Fluoxetine. Tell your doctor if you take every other medicines, especially any in the following:

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• Anorexiants (eg, phentermine), fenfluramine derivatives (eg, dexfenfluramine), linezolid, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), St. John's wort, trazodone, or tryptophan because severe unwanted effects, like a reaction that will include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur

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• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) for the reason that risk of bleeding, including stomach bleeding, might be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) since the risk of low blood sodium levels might be increased

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• Tramadol since the chance of seizures could possibly be increased

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• Cyclobenzaprine or H₁ antagonists (eg, astemizole, terfenadine) because severe cardiovascular disease, including irregular heartbeat, may occur

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• HIV protease inhibitors (eg, ritonavir) given that they may increase the risk of Fluoxetine's negative effects

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• Cyproheptadine since it may decrease Fluoxetine's effectiveness

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• Aripiprazole, benzodiazepines (eg, alprazolam), beta-blockers (eg, propranolol), carbamazepine, clozapine, dextromethorphan, digoxin, flecainide, haloperidol, hydantoins (eg, phenytoin), lithium, norepinephrine reuptake inhibitors (eg, atomoxetine), phenothiazines (eg, chlorpromazine, thioridazine), pimozide, propafenone, risperidone, tricyclic antidepressants (eg, amitriptyline), or vinblastine for the reason that chance of their unwanted side effects could possibly be increased by Fluoxetine.

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This might not be a total listing of all interactions that may occur. Ask your doctor if Fluoxetine may connect to other medicines that you simply take. Check with your health care provider before starting, stop, or affect the dose associated with a medicine.

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Important safety information:

• Fluoxetine may cause drowsiness or dizziness. These effects could be worse if you go with alcohol or certain medicines. Take Fluoxetine with caution. Do not drive or perform other possible unsafe tasks unless you recognize how you reply to it.

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• Check using your doctor prior to deciding to consume alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you take Fluoxetine; it might enhance their effects. Ask the pharmacist if you have questions regarding which medicines could cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, improve your dose, or take Fluoxetine for over prescribed without checking along with your doctor.

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• Children and teenagers taking Fluoxetine might be at increased risk for suicidal thoughts or actions. Adults can also be affected. The risk could be greater in patients who have had suicidal thoughts or actions inside the past. The risk may also be greater in patients who've had bipolar (manic-depressive) illness, or if their family members have experienced it. Watch patients taking Fluoxetine closely. Contact a doctor at the same time if new, worsened, or sudden symptoms including depressed mood; anxious, restless, or irritable behavior; panic and anxiety attacks; or any unusual difference in mood or behavior occur. Contact your physician straight away if any signs of suicidal thoughts or actions occur.

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• Diabetes patients - Fluoxetine may affect your blood glucose. Check blood sugar levels levels closely. Ask your physician before you decide to change the dose of your respective diabetes medicine.

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• Serotonin syndrome is really a possibly fatal syndrome that can be caused by Fluoxetine. Your risk could possibly be greater invest the Fluoxetine with certain other medicines (eg, MAOIs, SSRIs, "triptans"). Symptoms can sometimes include agitation; coma; confusion; hyperhidrosis; fast or irregular heartbeat; fever; hallucinations; nausea, vomiting, or diarrhea; tremor. Contact your doctor immediately when you have any of these symptoms.

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• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that could be due to Fluoxetine. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your medical professional immediately for those who have all of these symptoms.

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• If your doctor tells you to stop taking Fluoxetine, you will need to watch for many weeks before you begin to adopt certain other medicines (eg, MAOIs, nefazodone, thioridazine). Ask your doctor when you ought to start to take your new medicines after you might have stopped taking Fluoxetine.

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• Fluoxetine may rarely cause a prolonged, painful erection. This could happen even when you might be not having sexual intercourse. If this is not treated straight away, it could possibly cause permanent sexual dysfunctions for example impotence. Contact a medical expert right away in such a circumstance.

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• Fluoxetine contains some of the same ingredients as Prozac, medication utilized to treat depression and also other mental problems, and Symbyax, medicine used to treat depression in patients with bipolar disorder. Do not take Fluoxetine if you happen to be also taking Prozac or Symbyax. Discuss any queries or concerns using your doctor.

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• Use Fluoxetine with caution inside the elderly; they could possibly be more understanding of its effects, especially low blood sodium levels.

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• Caution is advised when you use Fluoxetine in kids; they might be more understanding of its effects, especially increased risk of suicidal thoughts or actions.

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• Fluoxetine ought to be used in combination with careful attention in children; safety and effectiveness in children are not confirmed.

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• Fluoxetine may cause weight changes. Children and teenagers may need regular weight and growth checks since they take Fluoxetine.

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• Pregnancy and breast-feeding: Fluoxetine could potentially cause harm to the fetus if it is employed over the last a few months of childbearing. If you get pregnant, contact your doctor. You will need to discuss the rewards and perils associated with using Fluoxetine while you happen to be pregnant. Fluoxetine is located in breast milk. Do not breastfeed while you are taking Fluoxetine.

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