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This medication is utilized to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, better help you sleep, and increase your power level. This medicine belongs to a class of medications called antidepressants that are tricyclic. It works by affecting the balance of certain natural chemicals (neurotransmitters such as for instance serotonin) within the brain.

DIFFERENT USES: This section contains uses of the medication that aren't listed in the approved labeling that is professional the drug but that could be recommended by your wellbeing care expert. Make use of this drug for a condition which is listed in this section just if it's been so recommended by your health care professional.

This medication might also be used to treat neurological pain (such as peripheral neuropathy, postherpetic neuralgia), consuming disorder (bulimia), other mental/mood problems (such as anxiety, panic disorder), or to avoid migraine headaches.

How to use Endep

Read the Medication Guide supplied by your pharmacist you get a refill before you start taking amitriptyline and each time. If you have any relevant questions, check with your physician or pharmacist.

Take this medicine by lips, frequently 1 to 4 times daily or as directed by your physician. If you take it only once a day, take it at bedtime to help reduce daytime sleepiness. The dosage is based on your medical condition and response to therapy.

To reduce your threat of side results (such as for example drowsiness, dry lips, dizziness), your doctor may direct you to definitely start this medicine at a low dose and slowly increase your dose. Follow your doctor's instructions carefully.

Take this medication regularly so that you can obtain the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or use this drug more usually or for longer than prescribed. Your condition shall not improve any faster, and your risk of part effects will increase.

It is critical to continue taking this medicine also should you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is unexpectedly stopped. Also, you might experience symptoms such as mood swings, headache, tiredness, and sleep change. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your pharmacist or doctor for lots more details. Report any new or worsening symptoms right away.

This medication may not away work right. You may see some benefit within a week. However, it may take up to 4 weeks before you feel the full effect.

Tell your physician if your condition persists or worsens (such as your feelings of sadness become worse, or perhaps you have thoughts of committing suicide).

Part Effects

See section that is also warning.

Drowsiness, dizziness, dry lips, blurred eyesight, constipation, fat gain, or trouble urinating may occur. If any of these effects persist or worsen, notify your pharmacist or doctor promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or position that is lying.

To ease dry mouth, suck on (sugarless) difficult candy or ice potato chips, chew (sugarless) gum, drink water, or use a saliva substitute.

To avoid constipation, keep a diet adequate in fiber, beverage plenty of water, and exercise. In the event that you become constipated while by using this medication, consult your pharmacist for help in selecting a laxative.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious adverse effects.

Inform your doctor right away if any of the rare but serious adverse effects occur: easy bruising/bleeding, persistent heartburn, shaking, mask-like facial expressions, muscle spasms, severe stomach/abdominal discomfort, decreased sexual ability/desire, enlarged/painful breasts.

Get help that is medical away if you have actually any very serious adverse effects, including: black stools, vomit that seems like coffee grounds, severe dizziness, fainting, seizures, attention pain/swelling/redness, vision modifications (such as seeing rainbows around lights at evening).

This medication may rarely cause a very serious condition called neuroleptic cancerous syndrome (NMS). Get medical help straight away for those who have any of the following signs: fever, muscle stiffness, severe confusion, perspiring, fast/irregular heartbeat.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a critical hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This is certainly not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Into the US -

Call your doctor for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side effects. You may report effects that are side Health Canada at 1-866-234-2345.


See section that is also warning.

Before taking amitriptyline, inform your medical practitioner or pharmacist if you are allergic to it, or to other tricyclic antidepressants (such as nortriptyline), or if you have any other allergies. This product may contain inactive ingredients, that may cause allergic reactions or other issues. Talk to your pharmacist for lots more details.

Before applying this medication, tell your physician or pharmacist your medical history, especially of: bleeding problems, breathing problems, liver problems, recent heart attack, problems urinating (such as as a result of enlarged prostate), overactive thyroid (hyperthyroidism), personal or genealogy and family history of glaucoma (angle-closure type), personal or genealogy of mental/mood conditions (such as manic depression, psychosis), family history of suicide, seizures, conditions that will increase your threat of seizures (such as other brain infection, alcohol withdrawal).

Amitriptyline may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention straight away.

The possibility of QT prolongation can be increased when you yourself have specific medical conditions or are taking other drugs that may cause QT prolongation. Before utilizing amitriptyline, tell your doctor or pharmacist of all medications you take and in the event that you have actually some of the following conditions: certain heart related illnesses (heart failure, sluggish heartbeat, QT prolongation in the EKG), family members history of certain heart related illnesses (QT prolongation in the EKG, unexpected cardiac death).

Minimal degrees of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your doctor about utilizing amitriptyline properly.

This drug may make you drowsy or dizzy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid beverages that are alcoholic.

Before having surgery, tell your doctor or dental practitioner about all the products you use (including prescribed drugs, nonprescription drugs, and herbal products).

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective outside.

It harder to control your blood sugar levels if you have diabetes, this drug may make. Monitor your blood sugar levels regularly and tell your doctor of the results. Your doctor might require to adjust your diabetes medicine, exercise program, or diet.

Older grownups may be much more sensitive to the adverse effects of the drug, especially dry mouth, dizziness, drowsiness, confusion, constipation, difficulty urinating, and QT prolongation (see above). Dizziness, drowsiness, and confusion can raise the risk of dropping.

During pregnancy, this medication should be utilized only when obviously needed. Discuss the risks and benefits with your physician.

Since untreated mental/mood issues (such as for instance depression, anxiety, panic disorder) can be a serious condition, do not stop using this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and the consequence on a nursing infant is unknown. Check with your doctor before breast-feeding.

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