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Precautions

Do NOT use Tamoxifen if:

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• you might be allergic to your ingredient in Tamoxifen

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• you are choosing Tamoxifen to relieve your risk of breast cancers along with past blood clots inside the lung or leg

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• you are employing Tamoxifen to cut back your risk of breast cancers and yourself take certain anticoagulants (eg, warfarin)

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• you take anastrozole.

Contact a medical expert or health care provider straight away if some of these apply to you.

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Some health conditions may talk with Tamoxifen. Tell your medical professional or pharmacist if you have any medical conditions, particularly if any of the following sign up for you:

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• if you might be pregnant, planning to become pregnant, or are breast-feeding

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• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines, foods, or any other substances

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• for those who have a medical history of blood clots in the legs or lungs

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Some medicines may connect to Tamoxifen. Tell your medical provider if you take another medicines, especially any of the following:

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• Anticoagulants (eg, warfarin) because potential risk of bleeding may be increased

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• Cytotoxic cancer medicines (eg, cisplatin) because potential risk of developing blood clots could be increased

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• Rifampin as it may decrease Tamoxifen's effectiveness

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• Fluorouracil or mitomycin C since they may increase the risk of Tamoxifen's unwanted effects

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• Aromatase inhibitors (eg, anastrozole, letrozole) as their effectiveness might be decreased by Tamoxifen.

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This may not be an entire set of all interactions which could occur. Ask your medical provider if Tamoxifen may talk with other medicines that you take. Check with your medical provider prior to starting, stop, or change the dose of any medicine.

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Important safety information:

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• Tamoxifen may cause dizziness. These effects may be worse if you get it with alcohol or certain medicines. Use Tamoxifen with caution. Do not drive or perform other possible unsafe tasks and soon you understand how you react to it.

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• Tamoxifen may lessen the quantity of clot-forming cells (platelets) with your blood. Avoid activities that might cause bruising or injury. Tell a medical expert if you have unusual bruising or bleeding. Tell your physician when you have dark, tarry, or bloody stools.
• Tamoxifen may lower the ability of one's body to fight infection. Avoid connection with those who have colds or infections. Tell your doctor possibly indications of infection like fever, sore throat, rash, or chills.

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• New tumors have happened in body sites apart from the uterus in patients taking Tamoxifen. It is unknown if Tamoxifen may be the cause. Discuss questions or concerns together with your doctor.

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• Women taking Tamoxifen to relieve the chance of breast cancer really should have a breast exam, mammogram, and gynecological exam before commencing and during treatment with Tamoxifen.

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• Women who may get pregnant has to start taking Tamoxifen within a menstrual period. Women who have irregular menstrual periods really should have a pregnancy test immediately before commencing Tamoxifen. Talk to your physician when you have questions about how exactly to begin with taking Tamoxifen.

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• Women who may conceive must use effective nonhormonal contraception (eg, condoms, diaphragm) during intercourse while they are taking Tamoxifen as well as 8 weeks when they stop taking it. Do not use hormonal birth control method (eg, contraception pills); may possibly not work as well as you take Tamoxifen. Discuss questions about effective nonhormonal contraceptive with your doctor.

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• Tamoxifen will not stop you from getting pregnant.

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• Lab tests, including breast exams, mammograms, gynecologic exams, complete blood counts, and liver function tests, could possibly be performed as you use Tamoxifen. These tests could possibly be used to monitor your complaint or look for negative effects. Be sure to keep all doctor and lab appointments.
• Tamoxifen must be in combination with extreme care in youngsters; safety and effectiveness in kids haven't been confirmed.

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• Pregnancy and breast-feeding: Tamoxifen may cause harm to the fetus. Do not get pregnant whilst you are employing it as well as for 2 months as soon as you stop using it. If you think you could possibly be pregnant, contact your doctor. You will need to discuss the huge benefits and risks of using Tamoxifen while you might be pregnant. It is not known if Tamoxifen can be found in breast milk. Do not breastfeed while taking Tamoxifen.

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