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INDICATIONS

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Detrol is indicated to the management of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol the same manner prescribed by your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to ensure that you get the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill may cause excessive drug to be removed at one time.

Store Detrol at room temperature from moisture and also heat.

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If you missed a dose - make missed dose when you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to create up the missed dose.

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DOSAGE

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The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose might be lowered to 2 mg daily depending on individual response and tolerability; however, limited efficacy data are around for Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol just isn't appropriate for use in patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min haven't been studied and employ of Detrol within this population just isn't recommended.

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For patients who are taking drugs that are potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store far from heat, moisture, and light. Do not store in the bathroom. Keep Detrol out of your reach of kids and from pets.

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Side Effects

Get emergency medical help for those who have any of these warning signs of a hypersensitivity to Detrol: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Stop using Detrol and call your physician at once for those who have any of these serious unwanted side effects:

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Less serious Detrol negative effects might include:

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This is not a complete listing of unwanted side effects while others may occur. Call a medical expert for health advice about unwanted effects.

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Precautions

Before taking tolterodine, tell your medical professional or pharmacist in case you are allergic with it; or in case you have every other allergies. This product may contain inactive ingredients, which could cause allergic reactions or any other problems. Talk to your pharmacist for additional information.

This medication should not be used for those who have certain health conditions. Before by using this medicine, consult your doctor or pharmacist in case you have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), a particular eye condition (uncontrolled narrow-angle glaucoma).

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Before by using this medication, tell a medical expert or pharmacist your medical history, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, a specific muscle disease (myasthenia gravis).

Tolterodine might cause a condition that affects the guts rhythm (QT prolongation). QT prolongation can infrequently lead to serious (rarely fatal) fast/irregular heartbeat along with other symptoms (for example severe dizziness, fainting) that require immediate medical assistance. The chance of QT prolongation could be increased for those who have certain medical conditions or are taking other drugs that may affect the guts rhythm (see also Drug Interactions section). Before using tolterodine, tell your doctor or pharmacist for those who have these things conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation inside EKG), genealogy and family history of certain heart related illnesses (QT prolongation within the EKG, sudden cardiac death).

Low numbers of potassium or magnesium within the blood may also increase your risk of QT prolongation. This risk may increase the use of certain drugs (for example diuretics/"water pills") or for those who have conditions for example severe sweating, diarrhea, or vomiting. Talk to your doctor about using tolterodine safely.

This drug will make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or go activity that requires alertness or clear vision before you are sure it is possible to perform such activities safely. Limit alcohol based drinks.

This medication might cause decreased sweating. Avoid becoming overheated in summer, saunas, or during exercise or any other strenuous activities since heatstroke may occur.

Kidney function declines when you age. This medication is removed with the kidneys. Therefore, elderly people could possibly be more sensitive to this drug.

This medication ought to be used not until clearly needed during pregnancy. It just isn't known whether Detrol will harm an baby. Tell your physician should you be pregnant or prefer to get pregnant while using this medication. Discuss the risks and benefits with your physician.

It is unknown if this drug passes into breast milk. Consult your physician before breast-feeding.

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