This medication is employed to avoid or treat gout assaults (flares). Usually gout signs develop abruptly and involve just one or a joints that are few. The toe that is big leg, or ankle joints are most often affected. Gout is caused by too much acid that is uric the blood. When acid that is uric within the bloodstream are way too high, the uric acid may form hard crystals in your joints. Colchicine works by decreasing swelling and lessening the create up of uric acid crystals that hurt into the affected joint(s).
This medication is also used to avoid attacks of pain within the abdomen, upper body, or joints caused by a specific inherited disease (familial Mediterranean fever). It really is thought to work by decreasing your production of a certain protein (amyloid A) that builds up in people with familial Mediterranean fever.
Colchicine is not a discomfort medication and should not be used to relieve other causes of pain.
DIFFERENT USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that could be recommended by your health care professional. Use this drug for a condition that is listed in this section only if it has been therefore prescribed by your quality of life care professional.
This medication may also be used to reduce swelling and inflammation associated with sac that covers the surface of the heart, an ailment called pericarditis.
Read the Medication Guide provided by your pharmacist you get a refill before you start taking colchicine and each time. If you have any relevant concerns about the information, ask your medical practitioner or pharmacist.
Take this medication by mouth with or without meals, precisely as directed by your doctor. Dosing recommendations vary widely and may differ from the recommendations that are following. Taking more than the recommended dose might perhaps not increase this medication's effectiveness and could increase your risk for negative effects. Ask your pharmacist or doctor for more details.
If you're taking this medicine to treat a gout attack, follow the directions carefully given by your doctor. This medication works best at the first sign of an attack if you take it. The suggested dose is 1.2 milligrams at the first sign of an attack, followed by 0.6 milligrams one hour later. The maximum recommended dose is 1.8 milligrams taken over a 1-hour period. Ask your physician ahead of time about how soon you can repeat treatment with this specific medication if you have another gout attack.
You should follow if you are taking this medication to prevent gout attacks or for pericarditis, ask your doctor about the dose and schedule. Carefully follow your doctor's directions.
If you are taking this medication to prevent attacks of pain caused by familial Mediterranean fever, the usual dose is 1.2 to 2.4 milligrams daily. The total dose may be taken once day-to-day or divided into two doses a day. Your physician may need certainly to adjust your dose to control your symptoms or when you yourself have adverse effects.
The dosage is based on your condition that is medical drugs/foods you may be taking, and response to treatment. To reduce your risk for serious side effects, do not increase your dose, take it more frequently, or take it for a bit longer than directed by the medical practitioner. Severe side-effects may occur even at typical doses that are prescribed.
In case your medical practitioner directs one to just take colchicine regularly, use it regularly to obtain the most benefit from it. To help you remember, take it at the time( that is same) each day.
Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.
If you are taking this medication to treat symptoms due to familial Mediterranean fever, tell your doctor if your condition does not improve or if it worsens.
Diarrhoea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects persist or aggravate, tell your pharmacist or doctor promptly.
Keep in mind that your physician has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.
Stop taking this medication and get help that is medical away if any of these very serious negative effects happen: unusual bleeding/bruising, serious diarrhea or vomiting, muscle tissue weakness or pain, numbness/tingling in your fingers or toes, pale or grey color associated with lips/tongue/palms of fingers, indications of infection (such as for example fever, persistent sore throat), unusual weakness/tiredness, fast heartbeat, shortness of breath, change in the total amount of urine.
An extremely serious allergic reaction to this drug is rare. However, seek immediate attention that is medical you see any symptoms of a critical hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the usa -
Phone your doctor for medical advice about side-effects. You may possibly report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Phone your medical practitioner for medical advice about side effects. You'll report effects that are side Health Canada at 1-866-234-2345.
Before taking this medicine, inform your physician or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic responses or other problems. Speak with your pharmacist for additional information.
Before using this medication, tell your medical professional or pharmacist your history that is medical of: kidney problems, liver problems (such as cirrhosis).
Alcohol can decrease this drug's effectiveness. Limit alcohol while using this drug.
This medication can influence how well your body absorbs some meals and nutrients (such as for example vitamin B12). Consult with your doctor or pharmacist for more details.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the relative negative effects of this medication, especially muscle weakness/pain and numbness/tingling within their fingers or toes.
Colchicine can decrease production that is sperm which could impact the power of a male to father a youngster. Consult your medical practitioner for more information.
During maternity, this medication should be used only once clearly needed. Discuss the potential risks and benefits with your doctor.
This medication passes into breast milk. While there were no reports of damage to nursing infants, consult your medical professional before breast-feeding. Your doctor may suggest you take your medication apart from breast-feeding that you separate the time(s.
Airmail: 2-3 weeks, EMS: 3-8 business days.