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This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause scarring that is permanent.

OTHER USES: This area contains uses of this drug which are not detailed in the approved labeling that is professional the drug but that may be prescribed by your wellbeing care expert. Make use of this drug for a condition that is listed in this section as long as it has been so prescribed by your wellness care expert.

This medication can also be used to deal with a certain type of cancer (neuroblastoma).

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Read the Medication Guide given by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions regarding isotretinoin, consult your medical practitioner or pharmacist before taking the medicine.

Swallow capsules whole. Don't crush or chew them. Isotretinoin is often taken twice daily for 15-20 weeks, or as directed by your doctor. Directions for most generic forms of isotretinoin state that it should be taken with meals. Nonetheless, the FDA has indicated that the Absorica brand might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist for more information. Take this drug with a glass that is full of, and do not lie down for 10 minutes after taking it.

The dosage is dependant on your medical condition, weight, and response to treatment.

Your acne may worsen during the very first day or two of taking this drug, also it may occupy to 1-2 months before you spot the full benefit of this medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer will not suggest long-term use of isotretinoin. Usually do not take more than the recommended dose.

Since this drug may be absorbed through the skin and lungs and may harm an baby that is unborn women who are pregnant or who could become pregnant should not handle this medicine or breathe the dust from the capsules.

Unwanted Effects

Dry lips and mouth, minor inflammation of the eyelids or lips, crusty skin, nosebleeds, upset belly, or thinning of locks may happen. If some of these effects persist or aggravate, tell your doctor or pharmacist promptly.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Keep in mind that your particular doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious adverse effects.

Tell your doctor right away in the event that you have some of these not likely but serious adverse effects: mental/mood changes (e.g., depression, aggressive or violent behavior, as well as in unusual situations, thoughts of committing suicide), tingling feeling in your skin, quick/severe sunburn (sun sensitiveness), back/joint/muscle discomfort, signs of disease (e.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.

Isotretinoin may rarely cause disease of this pancreas (pancreatitis) that may seldom be deadly. Stop taking this medication and tell your physician right away if you develop: severe stomach pain, severe or persistent nausea/vomiting.

Stop taking this medication and tell your doctor right away if you develop these not likely but very serious adverse effects: serious headache, eyesight modifications, tinnitus, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhea, anal bleeding.

A very serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you notice any outward symptoms of a critical allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Into the US -

Phone your physician for medical advice about side-effects. You might report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about adverse effects. You could report adverse effects to wellness Canada at 1-866-234-2345.


Before taking isotretinoin, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergic reactions or other dilemmas. Some people who are sensitive to peanuts may be allergic to also soy. Talk to your pharmacist for more information.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate bloodstream while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outside.

Isotretinoin make a difference your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your medical practitioner for more information.

Do not have cosmetic procedures to smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring might occur.

Avoid the use of alcohol while taking this medication because it might increase the risk of certain unwanted effects (e.g., pancreatitis).

Restricted information suggests isotretinoin might cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal plate closing). Check with your physician for more details.

Care is advised when using this medication into the elderly because they may be more painful and sensitive to its results, particularly the impacts on bones.

Caution is advised when working with this drug in children because they might be more responsive to its results, specially back/joint/muscle pain.

This medication should not be used during pregnancy or by those that may become pregnant during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See section that is also warning.

Since this drug may be absorbed through skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

You'll want two pregnancy that is negative before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is positive, you must stop taking this medication and consult your doctor right away.

It really is unknown if this medication passes into breast milk. Nevertheless, similar drugs pass into breast milk. Breast-feeding while by using this medication is not recommended. Consult your physician before breast-feeding.

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