This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing oil that is facialsebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause permanent scarring.

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OTHER USES: This area contains uses of this drug being not listed in the approved labeling that is professional the drug but that will be prescribed by your health care professional. Utilize this drug for a condition that is listed in this section only when it has been so prescribed by your wellness care expert.

This medicine can also be used to take care of a certain type of cancer (neuroblastoma).

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Read the Medication Guide supplied by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult your doctor or pharmacist before taking the medication.

Swallow capsules whole. Usually do not crush or chew them. Isotretinoin is frequently taken twice daily for 15-20 weeks, or as directed by your physician. Directions for many generic forms of isotretinoin state that it ought to be taken with meals. Nonetheless, the FDA has indicated that the Absorica brand name might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your pharmacist or doctor for lots more information. Take this drug with a full glass of water, and do not lie down for 10 mins after taking it.

The dosage is dependant on your medical condition, weight, and reaction to treatment.

Your acne may worsen throughout the very first few days of using this medication, and it may take up to 1-2 months before you notice the full benefit of this medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer will not recommend use that is long-term of. Usually do not take more than the recommended dose.

Since this drug could be consumed through the skin and lungs and may damage an baby that is unborn women who are pregnant or who can become pregnant should perhaps not handle this medicine or breathe the dust from the capsules.

Side Effects

Dry lips and lips, minor inflammation of the eyelids or lips, crusty epidermis, nosebleeds, upset belly, or thinning of locks may take place. If any of these effects persist or aggravate, tell your pharmacist or doctor quickly.

To relieve dry mouth, suck on (sugarless) hard candy or ice potato chips, chew (sugarless) gum, drink water, or make use of a saliva substitute.

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Keep in mind your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have some of these unlikely but serious side effects: mental/mood changes (e.g., depression, aggressive or violent behavior, and in unusual situations, thoughts of suicide), tingling feeling in skin, quick/severe sunburn (sunlight sensitivity), back/joint/muscle pain, signs of infection (e.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may hardly ever cause disease associated with the pancreas (pancreatitis) that may hardly ever be fatal. Stop taking this medication and inform your medical practitioner straight away if you develop: serious stomach pain, serious or persistent nausea/vomiting.

Stop using this medication and tell your doctor right away if you develop these unlikely but very serious negative effects: serious headache, vision changes, ringing in the ears, hearing loss, chest discomfort, yellowing eyes/skin, dark urine, severe diarrhea, rectal blood.

A very serious allergic reaction to this drug is rare. However, seek immediate attention that is medical you notice any outward symptoms of a critical allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

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This isn't a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Within the US -

Call your physician for medical advice about side effects. You might report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your medical professional for medical advice about side effects. You could report effects that are side wellness Canada at 1-866-234-2345.


Before taking isotretinoin, tell your doctor or pharmacist in the event that you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergies or other dilemmas. Some people who are sensitive to peanuts may also be allergic to soy. Speak to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate blood after you stop taking it while you are taking isotretinoin and for at least 1 month.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

Isotretinoin can impact your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark you can perform such activities safely until you are sure.

You may not tolerate them as well as usual while using this medication if you wear contact lenses. Contact your medical practitioner for lots more information.

Do not have cosmetic procedures to smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring might occur.

Avoid making use of alcohol while taking this medication because it may increase the possibility of certain unwanted effects (e.g., pancreatitis).

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Restricted information shows isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal dish closure). Consult your physician for more details.

Caution is recommended when using this medication in the elderly because they might be more sensitive to its impacts, particularly the effects on bones.

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Caution is advised when working with this drug in children because they may be more sensitive to its results, especially back/joint/muscle pain.

This drug ought not to be used during pregnancy or by those that may become pregnant during treatment. If you become pregnant or think you may be pregnant, inform your doctor right away. See also Warning section.

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Since this drug could be absorbed through your skin and lungs and may harm an unborn baby, females that are pregnant or who may become expecting must not handle this medication or breathe the dust from the capsules.

You must have two negative pregnancy tests before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is positive, you must stop taking this medication and consult with your doctor right away.

It is unknown if this medication passes into breast milk. However, similar medications pass into breast milk. Breast-feeding while by using this drug is not recommended. Consult your medical practitioner before breast-feeding.

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