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Duloxetine is employed to take care of anxiety and depression. In addition, duloxetine is used to simply help relieve neurological pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical ailments such as arthritis, chronic back discomfort, or fibromyalgia (a state of being which causes widespread pain).

Duloxetine may improve your mood, rest, appetite, and degree of energy, and decrease nervousness. Additionally decrease pain as a result of certain conditions that are medical. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain substances that are naturalserotonin and norepinephrine) in mental performance.

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OTHER USES: This part contains uses of this medication which can be not listed in the approved professional labeling for the medication but which will be prescribed by your quality of life care expert. Use this drug for an ailment that is placed in this area only if it's been therefore recommended by your wellbeing care professional.

This medication could also be used to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist you get a refill before you start using duloxetine and each time. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your physician, usually 1 or 2 times a day with or without food. It may help to take this drug with food if you have nausea. Swallow the capsule whole. Do not crush or chew the capsule or mix the contents with food or liquid. Doing so can release all of the drug at once, increasing the risk of side effects.

The dosage is based on your age, condition and reaction to treatment. To lessen your risk of part effects, your doctor may direct you to definitely start this medicine at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the benefit that is most from it. To help you remember, simply take it during the same time(s) each time.

You should carry on taking this medication as prescribed even should you feel well. Do not stop taking this medication without consulting your physician. Some conditions could become worse whenever this drug is suddenly stopped. Additionally, you may experience symptoms such as for instance dizziness, confusion, mood swings, headache, tiredness, diarrhoea, sleep changes, and brief feelings much like electric shock. Your dose may gradually need to be decreased to reduce adverse impacts. Report any brand new or symptoms that are worsening away.

Inform your medical professional when your condition persists or worsens.

Side Effects

See section that is also warning.

Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any of these impacts persist or aggravate, tell your doctor immediately.

Dizziness or lightheadedness may occur, particularly when you start that is first increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or position that is lying.

Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total email address details are high.

Tell your doctor right away if some of these serious side results occur: confusion, easy bruising/bleeding, decreased interest in sex, alterations in sexual ability, muscle tissue cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease within the amount of urine, signs of liver problems (such as stomach/abdominal discomfort, persistent sickness, vomiting, yellowing eyes/skin, dark urine).

Get medical help straight away if you have got any extremely serious negative effects, including: black/bloody stools, vomit that seems like coffee grounds, seizure, attention pain/swelling/redness, vision changes (such as for example seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause an extremely condition that is serious serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away in the event that you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, serious nausea/vomiting/diarrhea, twitching muscle tissue, unexplained temperature, uncommon agitation/restlessness.

an extremely severe allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a significant allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, difficulty respiration, skin blisters, mouth sores.

This is certainly not a list that is complete of adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Call your doctor for medical advice about part effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may possibly report effects that are side Health Canada at 1-866-234-2345.


Before taking duloxetine, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or. This product may contain ingredients that are inactive that may cause allergic reactions or other problems. Confer with your pharmacist to get more details.

Before using this medication, inform your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for instance bipolar/manic-depressive disorder), personal or family history of suicide attempts, bleeding problems, personal or household history of glaucoma (angle-closure type), high blood pressure, renal disease, liver disease, seizure disorder, stomach problems (such as slow emptying of the stomach), use/abuse of alcohol.

This medication might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid alcoholic beverages.

For those who have diabetes, duloxetine may affect your blood sugar. Check always your blood sugar levels frequently as directed by the doctor. Your physician may need to adjust your diabetes medication, exercise regime, or diet.

Before having surgery, tell your physician or dentist about all of the services and products you employ (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more responsive to the relative adverse effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), particularly when they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can raise the threat of falling.

Young ones may be more delicate to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug. See also Warning.

During pregnancy, this medicine should be used only if clearly needed. It may harm an baby that is unborn. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle tightness, or constant crying. In the event that you notice any one of these symptoms in your newborn, promptly tell the doctor.

Since untreated mental/mood problems (such as depression, anxiety) is a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This medication passes into breast milk and may have effects that are undesirable a nursing infant. Check with your physician before breast-feeding.

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