Duloxetine can be used to treat depression and anxiety. In addition, duloxetine is used to help relieve neurological pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as for instance arthritis, chronic back pain, or fibromyalgia (a state of being which causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It may relieve pain due to particular medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain substances that are naturalserotonin and norepinephrine) in the brain.

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OTHER USES: This part contains uses of this medication being perhaps not placed in the approved professional labeling for the medication but that could be prescribed by your health care pro. Use this drug for a disorder that is placed in this area only if it has been therefore recommended by your health care professional.

This medicine could also be used to help treat other painful nerve conditions (neuropathic pain).

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Read the Medication Guide and, if available, the Patient Information Leaflet supplied by your pharmacist before you start using duloxetine and each time you get a refill. If you have any relevant questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your physician, usually 1 or 2 times a with or without food day. It may help to take this drug with food if you have nausea. Swallow the capsule whole. Do not crush or chew the capsule or mix the contents with liquid or food. Doing therefore can release all the drug at once, increasing the risk of side effects.

The dosage is based on your age, condition and response to treatment. To lessen your risk of side effects, your doctor may direct you to definitely start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly to get the most benefit from this. To greatly help you remember, just take it during the same time(s) each time.

It is important to carry on taking this medicine as prescribed even should you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become even worse when this drug is suddenly stopped. Also, you may experience observable symptoms such as for example dizziness, confusion, mood swings, hassle, tiredness, diarrhea, sleep changes, and brief emotions similar to electric shock. Your dose may need to be gradually decreased to reduce side effects. Report any new or symptoms that are worsening away.

Inform your medical professional in the event your condition persists or worsens.

Side Effects

See also Warning section.

Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any of these results persist or worsen, tell your medical professional promptly.

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Dizziness or lightheadedness might occur, especially once you first start or increase your dose of this drug. To reduce the risk of dizziness, lightheadedness, or falling, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

This medication might raise your blood pressure. Check your blood pressure regularly and tell your doctor if the total answers are high.

Tell your doctor right away if some of these serious part effects occur: confusion, easy bruising/bleeding, decreased interest in intercourse, alterations in sexual ability, muscle cramps/weakness, shaking (tremor), difficulty urinating, unusual decrease into the amount of urine, signs of liver problems (such as stomach/abdominal pain, persistent sickness, vomiting, yellowing eyes/skin, dark urine).

Get medical help right away if you've got any really serious unwanted effects, including: black/bloody stools, vomit that appears like coffee grounds, seizure, eye pain/swelling/redness, vision changes (such as for example seeing rainbows around lights at night, blurred vision).

This medication may increase serotonin and rarely cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the next symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, serious nausea/vomiting/diarrhea, twitching muscles, unexplained temperature, uncommon agitation/restlessness.

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an extremely severe reaction that is allergic this drug is rare. However, get help that is medical away if you notice any symptoms of a critical allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing, skin blisters, mouth sores.

That is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Phone your doctor for medical advice about part effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about part effects. You may possibly report effects that are side wellness Canada at 1-866-234-2345.


Before taking duloxetine, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or. This product may contain ingredients that are inactive which can cause allergies or other problems. Talk to your pharmacist to get more details.

Before applying this medication, inform your doctor or pharmacist your medical history, especially of: personal or family history of psychiatric disorders (such as for instance bipolar/manic-depressive condition), personal or family history of suicide attempts, bleeding issues, personal or family history of glaucoma (angle-closure type), high blood pressure, renal disease, liver disease, seizure disorder, stomach problems (such as slow emptying for the stomach), use/abuse of alcohol.

This medication may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

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For those who have diabetes, duloxetine may affect your blood sugar levels. Check always your blood sugar levels regularly as directed by the doctor. Your medical professional might require to adjust your diabetes medication, exercise program, or diet.

Before having surgery, tell your physician or dentist about all the items you use (including prescription drugs, nonprescription medications, and herbal products).

Older adults may be more responsive to the relative side effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are taking "water pills" (diuretics). Dizziness, lightheadedness, or loss of coordination can boost the risk of falling.

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Young ones may be more delicate to the relative side effects of this drug, especially loss of appetite and weight loss. Monitor height and weight in children that are taking this drug. See also Warning.

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During pregnancy, this medication should really be used only if clearly needed. It may harm an baby that is unborn. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may develop withdrawal symptoms rarely such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

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Since untreated mental/mood issues (such as despair, anxiety) can be a condition that is serious do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

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This medication passes into breast milk and may have undesirable effects on a nursing infant. Check with your medical practitioner before breast-feeding.

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