Clomipramine is used to deal with obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living.
This medication belongs to a course of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain substances that are naturalserotonin, and others) in the brain.
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DIFFERENT USES: This section contains uses of the medication which can be not placed in the approved labeling that is professional the drug but which may be prescribed by your health care professional. Make use of this drug for a condition that is listed in this area only if it has been so prescribed by your health care professional.
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This medication has also been utilized to treat depression, panic assaults, and ongoing pain.
Read the Medication Guide available from your pharmacist. Check with your doctor or pharmacist if you have any concerns.
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Take this medication by mouth with or without food as directed by your physician. To reduce side-effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Often, the daily dose will not be more than 250 milligrams for grownups and 200 milligrams for young ones and teenagers.
Follow your physician's instructions very carefully. Never just take pretty much medication or frequently take it more than prescribed. Your condition shall not improve any faster and your threat of side effects such as for example seizures may be increased. Dosage is dependant on your medical condition and response to therapy.
Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for additional information.
Make use of this medication regularly in order to obtain the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each day.
Do not suddenly stop using this medication without consulting your physician. Some conditions may become even worse when the drug is suddenly stopped. You may experience sweating, dizziness, sickness, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may gradually need to be decreased.
It might just take 2 to 3 months or longer before the complete aftereffects of this medication are noticed. Inform your physician if your condition persists or if it worsens.
See section that is also warning.
Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily worsen when you initially start taking clomipramine. If any of these effects persist or worsen, notify your doctor or pharmacist quickly.
To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or make use of a saliva substitute.
To prevent constipation, maintain a meal plan adequate in dietary fiber, drink plenty of water, and workout. If you become constipated while by using this drug, consult with your pharmacist for aid in selecting a laxative (e.g., stimulant-type with stool softener).
Keep in mind that your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.
Tell your physician right away if some of these unlikely but serious side effects occur: mental/mood modifications (e.g., confusion, depression, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual periods, muscle tissue stiffness, ringing within the ears, sexual issues (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling for the hands/feet, trouble urinating.
Tell your physician straight away if any of these rare but really side that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially for the tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.
This medication may increase serotonin and seldom cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away in the event that you develop a few of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
Get help that is medical away in the event that you have very serious side effects, including: black stools, upper body discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights at night).
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially associated with the face/tongue/throat), severe dizziness, trouble breathing.
It is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
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Phone your physician for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
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Before taking clomipramine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other issues. Speak to your pharmacist for more information.
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Before making use of this medication, tell your doctor or pharmacist your medical history, especially of: bloodstream dilemmas (age.g., purpura, thrombocytopenia), difficulty in breathing (e.g., asthma, chronic bronchitis), personal or family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal dilemmas (e.g., chronic constipation, ileus), liver problems, renal dilemmas, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very serious reaction to specific medicines (neuroleptic malignant syndrome), heartburn/stomach acid within the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may increase your threat of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive treatment, brain injury/disease), certain kinds of tumors (e.g., pheochromocytoma, neuroblastoma).
Clomipramine may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The threat of QT prolongation are increased in the event that you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using clomipramine, inform your physician or pharmacist of all drugs you take and if you've got any of the next conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family reputation for certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the bloodstream may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your physician about using clomipramine safely.
This drug may make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit alcoholic beverages.
To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or lying position.
Before having surgery, tell your dentist or doctor that you're taking this medication.
Care is advised when utilizing this drug in children whom participate in active sports since it may increase the possibility of heart problems. (See also the Warning section.)
Older adults may be more sensitive to your relative side effects of this drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).
This medication should be used only when demonstrably needed during pregnancy. Newborns exposed to clomipramine during pregnancy may experience withdrawal symptoms or side effects. Inform your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
Since untreated mental/mood dilemmas (such as for example obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
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This drug passes into breast milk and may have effects that are undesirable a nursing infant. Consult your doctor before breast-feeding.
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