Clomipramine is used to treat obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.
This medication belongs to a class of medicines called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, amongst others) in the mind.
DIFFERENT USES: This area contains uses with this drug which are not placed in the approved professional labeling for the drug but that may be prescribed by the medical care professional. Make use of this drug for a condition that is listed in this section only if it was so prescribed by your health care professional.
This medication has additionally been utilized to treat depression, panic attacks, and pain that is ongoing.
Read the Medication Guide available from your own pharmacist. Consult your doctor or pharmacist if you have any questions.
Take this medication by mouth with or without meals as directed by your physician. To minimize unwanted effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Usually, the daily dose will not be more than 250 milligrams for grownups and 200 milligrams for children and teenagers.
Follow your doctor's guidelines very carefully. Usually do not take more or less medication or take it more frequently than prescribed. Your condition will not improve any faster and your risk of adverse effects such as seizures may be increased. Dosage is founded on your medical condition and response to therapy.
Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more information.
Make use of this medication regularly in purchase to get the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.
Do not suddenly stop using this medication without consulting your doctor. Some conditions may be even worse when the drug is suddenly stopped. You might experience sweating, dizziness, sickness, vomiting, headache, or irritability if you unexpectedly stop taking this drug. Your dose may need to be gradually decreased.
It might just take 2 to 3 months or longer ahead of the complete aftereffects of this medication are noticed. Inform your physician if for example the condition persists or if it worsens.
See section that is also warning.
Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily worsen when you initially start clomipramine that is taking. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
To alleviate mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva substitute.
To prevent constipation, maintain a meal plan sufficient in dietary fiber, drink plenty of water, and exercise. If you feel constipated while applying this drug, check with your pharmacist for aid in selecting a laxative (age.g., stimulant-type with stool softener).
Keep in mind that your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.
Tell your physician right away if some of these unlikely but side that is serious occur: mental/mood modifications (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk production, irregular/painful menstrual periods, muscle stiffness, ringing in the ears, sexual issues (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling of this hands/feet, difficulty urinating.
Tell your doctor straight away if any of these rare but extremely serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially of this tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.
This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop a few of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.
Get medical help right away if you have very severe part effects, including: black stools, upper body discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights at night).
An extremely serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially regarding the face/tongue/throat), severe dizziness, trouble breathing.
This isn't a complete list of possible adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In the usa -
Call your doctor for medical advice about adverse effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your physician for medical advice about unwanted effects. You may report effects that are side Health Canada at 1-866-234-2345.
Before taking clomipramine, tell your physician or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergy symptoms or other dilemmas. Speak to your pharmacist for additional information.
Before by using this medicine, tell your doctor or pharmacist your medical background, especially of: bloodstream problems (age.g., purpura, thrombocytopenia), difficulty in breathing (e.g., asthma, chronic bronchitis), personal or genealogy of glaucoma (angle-closure type), eating disorders (e.g., bulimia), heart issues (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal issues (e.g., chronic constipation, ileus), liver problems, renal dilemmas, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very severe a reaction to specific medications (neuroleptic malignant syndrome), heartburn/stomach acid in the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may boost your threat of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive treatment, mind injury/disease), particular kinds of tumors (e.g., pheochromocytoma, neuroblastoma).
Clomipramine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention straight away.
The danger of QT prolongation are increased if you have certain conditions that are medical are using other drugs that could cause QT prolongation. Before using clomipramine, tell your physician or pharmacist of the many drugs you are taking and when you've got any one of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the bloodstream may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your physician about making use of clomipramine safely.
This drug may make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.
To decrease dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
Before having surgery, tell your dentist or doctor that you are taking this medication.
Care is recommended when using this medication in children who take part in active sports since it may increase the risk of heart problems. (See also the Warning section.)
Older grownups may be more painful and sensitive to the relative negative effects of the drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).
This medication should be used only when demonstrably needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or side-effects. Inform your doctor immediately in the event that you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
Since untreated mental/mood dilemmas (such as obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.
This drug passes into breast milk and may have effects that are undesirable a nursing infant. Consult your doctor before breast-feeding.
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