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Uses

See also Warning section.

Promethazine is utilized to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It could be utilized that will help you feel sleepy/relaxed before and after surgery or even to help certain narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold.

Promethazine is an antihistamine and works by blocking a particular natural substance (histamine) that your body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as for instance acetylcholine) and by acting entirely on particular areas of the brain.

Cough-and-cold services and products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children more youthful than 6 years unless specifically directed by the doctor. Some items (such as long-acting tablets/capsules) are maybe not recommended for use in children younger than 12 years. Pose a question to your doctor or pharmacist for more details about using your product safely.

These services and products don't cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, follow all dosage carefully guidelines. Usually do not give other medication that is cough-and-cold might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

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Read the Patient Suggestions Leaflet if available from your own pharmacist before you start taking promethazine and each time you get a refill. If you have any relevant questions, ask your physician or pharmacist.

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Take this medication by mouth with or without food as directed by your doctor, frequently 2 to 4 times day-to-day. The first dose of promethazine should be taken 30 to 60 minutes before beginning travel for motion sickness. For allergies, this medication may be taken once daily at bedtime to avoid drowsy that is being the day. When used before surgery, promethazine may be taken the before or just before the procedure and may be continued afterwards as directed night.

If you should be using the liquid form of this medication, very carefully gauge the dosage utilizing a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

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The dosage is situated on your age, medical condition, and response to treatment. In children, the dosage can also be according to weight. Do not increase your dose and take this medication more often than directed.

Tell your doctor if your problem does not enhance or if it worsens.

Side Effects

Drowsiness, dizziness, constipation, blurred vision, or dry mouth may occur. If any of these results persist or aggravate, tell your physician.

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To alleviate dry mouth, suck (sugarless) difficult candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Keep in mind that your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Tell your doctor immediately in the event that you have any serious side-effects, including: fainting, sluggish heartbeat, mental/mood changes (such as hallucinations, nervousness, irritability, restlessness, confusion), unusual/uncontrolled movements (such as fixed upward stare, neck twisting, tongue movements), shaking (tremor), difficulty urinating, easy bleeding/bruising, signs of infection (such as fever, persistent sore throat), severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin.

Get medical help right away if you have any very severe part impacts, including: slow/shallow breathing, seizures.

This medication may rarely cause a very condition that is serious neuroleptic malignant syndrome (NMS). Get help that is medical away if you have got some of the after signs: temperature, muscle stiffness/pain/tenderness/weakness, severe tiredness, serious confusion, sweating, fast/irregular heartbeat, dark urine, improvement in the total amount of urine.

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A tremendously serious allergic reaction to this drug is rare. However, get medical help right away if you notice any observeable symptoms of a significant allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, difficulty breathing.

That is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Phone your doctor for medical advice about side impacts. You may report side effects to Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Phone your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

See also Warning section.

Before taking promethazine, tell your doctor or pharmacist in the event that you are allergic to it; or to any other phenothiazines (such as prochlorperazine); or if you have any other allergies. This product may contain inactive ingredients, which could cause sensitive responses or other problems. Speak with your pharmacist for lots more details.

Before applying this medication, inform your physician or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease-COPD, anti snoring), blood/immune system dilemmas (such as bone tissue marrow depression), high stress into the attention (glaucoma), heart disease (such as irregular heartbeat), high blood pressure, liver disease, specific brain disorders (such as neuroleptic malignant syndrome, Reye's syndrome, seizures), stomach/intestine problems (such as blockage, ulcer), overactive thyroid (hyperthyroidism), difficulty urinating (for instance, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.

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Before having surgery, tell your medical practitioner or dentist about all these products you utilize (including prescription drugs, nonprescription drugs, and herbal products).

Promethazine may make you more sensitive to the sunlight. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective out-of-doors.

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This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. Once the weather is hot, drink a complete lot of fluids and dress lightly. If you overheat, quickly look for a accepted place to cool down and sleep. Get medical help right away if you have a fever that does not disappear completely, mental/mood changes, headache, or dizziness.

Liquid products may include sugar and/or liquor. Caution is advised you to limit/avoid these substances in your diet if you have diabetes, liver disease, or any other condition that requires. Ask your doctor or pharmacist about using this item properly.

Children may become more delicate to the side effects of this drug, particularly slowed respiration (see alert section). This drug can often cause excitement in young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a complete lot of fluid (dehydration), people who have actually a family reputation for sudden infant death problem (SIDS), and those who are difficult to wake up from sleep.

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Older adults may be more sensitive to the relative side effects of this drug, especially drowsiness, confusion, constipation, or difficulty urinating. Drowsiness and confusion can increase the possibility of falling.

During pregnancy, this medicine ought to be used only when demonstrably needed. Talk about the risks and benefits along with your medical practitioner.

Its unknown if promethazine passes into breast milk. It could have effects that are undesirable a nursing infant. Check with your doctor before breast-feeding.

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