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This combination medication can be used to deal with symptoms of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) in the mind. Levodopa modifications into dopamine in mental performance, assisting to control movement. Carbidopa stops the breakdown of levodopa in the bloodstream therefore more levodopa can enter the mind. Carbidopa can additionally reduce some of levodopa's side effects such as vomiting and nausea.

Exactly how to use Sinemet

Take this medication by mouth with or without meals as directed by the doctor, usually three or four times each day.

Using this medication with food may help to decrease nausea. It is best to avoid a high-protein diet (it decreases the quantity of levodopa that your particular body takes in) during therapy, unless directed otherwise by the doctor. Separate your dosage of the medication by because hours that are many possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your doctor or pharmacist for more details.

The dosage is based on your condition that is medical and to treatment. To reduce your risk of adverse effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your physician's instructions carefully. This combination medication comes in various strengths with different amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor may also alone prescribe carbidopa to be studied with this combination.

Utilize this medicine regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some clients may experience a "wearing-off" (worsening of symptoms) ahead of the next dose is due. An "on-off" impact may additionally happen, in which unexpected short periods of stiffness occur. If these effects occur, contact your medical professional for feasible dosage adjustments which could help to lessen this effect.

Do not stop taking this medication without consulting your medical professional. Some conditions can become worse whenever this medication is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also Side Effects section.)

Inform your doctor should your condition does not improve or if it worsens.

adverse Effects

Dizziness, lightheadedness, sickness, vomiting, loss of appetite, trouble sleeping, unusual dreams, or headache may occur. If some of these effects persist or worsen, tell your doctor or pharmacist promptly.

This medication may cause saliva, urine, or perspiration to turn a dark color. This impact is safe, however your clothes might be stained.

To reduce the possibility of dizziness and lightheadedness, get up slowly when rising from a sitting or position that is lying.

Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.

Some people taking this medication have dropped asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some full cases, rest occurred without any emotions of drowsiness in advance. This sleep effect may occur anytime during therapy with carbidopa/levodopa regardless if you have used this medication for a time that is long. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor. Your danger of the sleep impact is increased by making use of liquor or other medicines that may make you drowsy. See also Precautions section.

Inform your physician right away if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get medical help right away if you have actually any very severe adverse impacts, including: upper body pain.

Suddenly stopping or reducing the dose of this medicine may seldom cause a really condition that is serious neuroleptic cancerous syndrome (NMS). Get medical help straight away if you have any of the following symptoms: temperature, uncommon muscle stiffness, serious confusion, sweating, fast/irregular heartbeat, quick breathing.

an extremely serious reaction that is allergic this drug is rare. However, get medical help right away in the event that you notice any symptoms of a critical allergic reaction, including: rash, itching/swelling (especially of this face/tongue/throat), serious dizziness, difficulty respiration.

This is maybe not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your medical professional for medical advice about side effects. You could report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about part impacts. You may report side effects to Health Canada at 1-866-234-2345.


Before using this medication, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Keep in touch with your pharmacist for lots more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, respiration problems (such as for instance asthma), heart disease (such as coronary attack, irregular heartbeat), kidney infection, stomach/intestinal ulcer, mental/mood disorders (such as depression, schizophrenia), blood disorders, seizures, sleep disorders.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit beverages that are alcoholic. See also adverse Impacts part.

Before having surgery, tell your doctor or dentist about all of the products you utilize (including prescription drugs, nonprescription drugs, and natural products).

During pregnancy, this medication should be used only if demonstrably required. Discuss the potential risks and benefits with your physician.

Levodopa passes into breast milk. It's unknown if carbidopa passes into breast milk. Consult with your medical practitioner before breast-feeding.

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