sinemet

Uses

This combination medication is used to deal with signs of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) in the mind. Levodopa changes into dopamine in the mind, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream therefore more levodopa can enter the brain. Carbidopa can additionally reduce some of levodopa's side effects such as nausea and vomiting.

How to use Sinemet

Take this medication by mouth with or without meals as directed by the doctor, often three or four times each and every day.

Taking this medication with food may help to decrease nausea. It is best to avoid a diet that is high-proteinit decreases the amount of levodopa that your particular body takes in) during therapy, unless directed otherwise by your doctor. Separate your dosage with this medication by as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for lots more details.

The dosage relies on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your doctor's instructions carefully. This combination medication comes in various strengths with different amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor could also prescribe carbidopa alone to be used with this combination.

Make use of this medicine regularly to get the most benefit from it. Each day to help you remember, take it at the same times.

Some patients may experience a "wearing-off" (worsening of symptoms) ahead of the next dose is due. An "on-off" effect may additionally happen, in which unexpected short periods of stiffness occur. If these effects occur, contact your physician for possible dose adjustments that may help to reduce this effect.

Do not stop taking this medication without consulting your medical professional. Some conditions could become even worse whenever this drug is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also unwanted effects part.)

Tell your physician when your condition does not enhance or if it worsens.

Side Effects

Dizziness, lightheadedness, sickness, vomiting, loss of appetite, difficulty sleeping, uncommon dreams, or headache may take place. If any of these effects persist or worsen, tell your pharmacist or doctor promptly.

This medication may cause saliva, urine, or sweat to turn a dark color. This impact is safe, but your clothes are stained.

To cut back the risk of dizziness and lightheadedness, get up slowly whenever rising from a sitting or position that is lying.

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Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Some people taking this medication have dropped asleep abruptly during their usual activities that are dailysuch as talking on the phone, driving). In some full instances, rest occurred without any feelings of drowsiness in advance. This sleep impact may occur anytime during therapy with carbidopa/levodopa regardless if you used this medication for a long time. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities. Your danger of this sleep effect is increased by making use of liquor or other medications that can make you drowsy. See also Precautions section.

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Inform your physician immediately if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get help that is medical away if you have actually any very serious side results, including: chest pain.

Abruptly stopping or reducing the dose of the medication may seldom cause a very serious condition called neuroleptic cancerous syndrome (NMS). Get medical help straight away for those who have any of the following symptoms: fever, uncommon muscle stiffness, severe confusion, perspiring, fast/irregular heartbeat, rapid breathing.

a very serious reaction that is allergic this drug is rare. However, get help that is medical away if you notice any outward symptoms of a serious allergic reaction, including: rash, itching/swelling (especially for the face/tongue/throat), serious dizziness, trouble breathing.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

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In the US -

Phone your physician for medical advice about unwanted effects. You might report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Phone your doctor for medical advice about part results. You may report side effects to Health Canada at 1-866-234-2345.

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Precautions

Before using this medication, tell your doctor or pharmacist in the event that you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergies or other problems. Communicate with your pharmacist for lots more details.

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Before applying this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, respiration problems (such as for instance asthma), heart disease (such as heart attack, irregular heartbeat), kidney condition, stomach/intestinal ulcer, mental/mood disorders (such as depression, schizophrenia), blood disorders, seizures, rest disorders.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit beverages that are alcoholic. See also Side Results part.

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Before having surgery, tell your doctor or dentist about most of the products you use (including prescription drugs, nonprescription drugs, and natural products).

During pregnancy, this medication should be utilized only when plainly needed. Discuss the risks and benefits with your physician.

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Levodopa passes into breast milk. It is unknown if carbidopa passes into breast milk. Consult your medical practitioner before breast-feeding.

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