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Precautions

Do NOT use Paxil if:

• you are allergic to your ingredient in Paxil
• you take or took linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort during the last 14 days
• you consider a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, fluoxetine), sibutramine, thioridazine, or tryptophan.

Contact your physician or physician immediately if these apply to you.

Some health conditions may interact with Paxil. Tell your doctor or pharmacist in case you have any medical conditions, in particular when any of the following sign up for you:

• if you are pregnant, likely to conceive, or are breast-feeding
• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines, foods, or other substances
• if you or a relative has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
• when you have a good reputation for seizures, cardiovascular disease, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems
• if you happen to be dehydrated, have low blood sodium levels, or consume alcohol
• if you will end up having electroconvulsive therapy (ECT).

Some medicines may connect to Paxil. Tell your doctor if you take every other medicines, especially any from the following:

• Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), another SSRI (eg, fluoxetine), St. John's wort, tramadol, trazodone, or tryptophan because severe unwanted effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur
• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) since the probability of bleeding, including stomach bleeding, might be increased
• Diuretics (eg, furosemide, hydrochlorothiazide) since the probability of low blood sodium levels may be increased
• Antiarrhythmics (eg, flecainide, propafenone, quinidine), H₁ antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe heart problems, including irregular heartbeat, may occur
• Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin since they may decrease Paxil's effectiveness
• Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) as the risk of their unwanted effects could be increased by Paxil
• Digoxin or tamoxifen because their effectiveness could possibly be decreased by Paxil.

This might not be a whole list of all interactions that may occur. Ask your medical provider if Paxil may communicate with other medicines that you take. Check with your doctor before starting, stop, or alter the dose of the medicine.

Important safety information:

• Paxil may cause drowsiness, dizziness, or blurred vision. These effects might be worse if you go on it with alcohol or certain medicines. Use Paxil with caution. Do not drive or perform other possible unsafe tasks before you discover how you react to it.
• Do not consume alcohol when you take Paxil.
• Check with your doctor before you use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Paxil; it might help to increase their effects. Ask your friendly phamacist when you have questions about which medicines could potentially cause drowsiness.
• Several weeks may pass before your symptoms improve. Do NOT take over the recommended dose, alter your dose, or use Paxil for longer than prescribed without checking with your doctor.
• Children, teenagers, and young adults taking Paxil might be at increased risk for suicidal thoughts or actions. Closely watch all patients taking Paxil. Contact a doctor at the same time if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual alternation in mood or behavior occur. Contact the physician right away if any signs of suicidal thoughts or actions occur.
• If a medical expert informs you to halt taking Paxil, you will need to await weeks prior to starting to look at certain other medicines (eg, MAOIs, nefazodone). Ask your physician when you should start to take a new medicines after you might have stopped taking Paxil.
• Paxil may rarely create a prolonged, painful erection. This could happen even when you are not making love. If this is not treated right away, it may lead to permanent sexual dysfunctions including impotence. Contact your doctor immediately if this happens.
• Serotonin syndrome is a possibly fatal syndrome that can be a result of Paxil. Your risk could possibly be greater for Paxil with certain other medicines (eg, "triptans," MAOIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; sweating in excess; and nausea, vomiting, or diarrhea. Contact your doctor at the same time if you have all of these symptoms.
• Neuroleptic malignant syndrome (NMS) is often a possibly fatal syndrome that could be caused by Paxil. Your risk may be greater if Paxil can be used with certain other medicines called antipsychotics (eg, aripiprazole, risperidone). Symptoms could be much like serotonin syndrome and might include fever, rigid muscles, hypertension changes, and mental changes. Contact your physician simultaneously when you have some of these symptoms.
• Use Paxil with caution within the elderly; they could be more sensitive to its effects, especially low blood sodium levels.
• Caution is recommended when working with Paxil in youngsters; they could be more understanding of its effects, especially increased chance of suicidal thoughts and actions.
• Paxil might cause weight changes. Children and teenagers might require regular weight and growth checks since they take Paxil.
• Pregnancy and breast-feeding: Paxil might cause problems for the fetus. If you conceive, get hold of your doctor. You will need to discuss the advantages and risks of using Paxil while you're pregnant. Paxil is situated in breast milk. If you happen to be or is going to be breast-feeding as you use Paxil, check using your doctor. Discuss any possible risks in your baby.