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Precautions

Do NOT use Coumadin if:

• you are allergic to any ingredient in Coumadin

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• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia

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• you might have active serious bleeding, bleeding inside the brain, certain blood vessel problems (eg, aneurysm, dissecting aorta), or inflammation or infection from the heart

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• you have active ulcer or bleeding with the stomach or bowel, urinary tract, genitals, or respiratory tract

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• you've got recently had or is going to be having eye, brain, or spinal-cord surgery; spinal puncture; spinal anesthesia; or any type of major surgery
• you are pregnant or may become pregnant

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• you are unable to have routine blood clotting tests
• you can't follow a medical expert's instructions properly and never have someone that will help you take your medicine
• you consider mifepristone, streptokinase, or urokinase.

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Contact your doctor or physician immediately if any of these apply to you.

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Some medical ailments may communicate with Coumadin. Tell your physician or pharmacist if you have any medical conditions, particularly if any with the following connect with you:

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• in case you are planning to get pregnant or are breast-feeding
• in case you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines or another substances
• for those who have recently been injured, fallen, given birth, or had surgery

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• in case you have a reputation stomach or bowel problems (eg, bleeding, ulcer, inflammation), cardiovascular disease (eg, heart failure, infection), blood clots, anemia or another blood problems (eg, protein C deficiency, high red blood cell levels), circulatory problems, or hypertension

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• if you have a good reputation for liver, kidney, or thyrois issues; yellowing with the skin or eyes; mental or mood problems; high cholesterol levels; arthritis; diabetes; or cancer
• for those who have poor nutrition, celiac disease, nutrient or fat absorption problems, or 'abnormal' amounts of vitamin K or vitamin C inside the blood, or in case you are drinking alcohol

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• when you have a fever, very poor health, diarrhea, fluid buildup, extra fat inside stools (steatorrhea), a recent or current infection, or tuberculosis, or in the event you will be confronted with high temperatures for the prolonged amount of time

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• if you have a heart valve replacement, an intrauterine device (IUD), or a catheter.

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Some medicines may interact with Coumadin. Tell your health care provider if you consider another medicines, especially any of the following:

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• Heparin or other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), salicylates (eg, aspirin), streptokinase, or urokinase because the risk of bleeding could be increased
• Mifepristone because excessive bleeding may occur
• Many prescription and nonprescription medicines (eg, used by infections, inflammation, aches and pains, hypertension, high cholesterol levels, seizures, mental or mood problems, diabetes, stomach or bowel irregularity, irregular heartbeat, birth control method, hormone replacement, cancer, and others), multivitamin products, and herbal or dietary supplements (eg, herbals, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may connect to Coumadin, increasing the chance of serious side effects including bleeding or blood clots.

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This will not be a complete set of all interactions that may occur. Ask your doctor if Coumadin may interact with other medicines which you take. Check with your health care provider before you begin, stop, or customize the dose of any medicine.

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Important safety information:

• Tell your physician or dentist that you simply take Coumadin prior to deciding to get any medical or dental treatments, emergency care, or surgery.
• Do NOT take a lot more than the recommended dose or use for over prescribed without checking with a medical expert. Contact a medical expert right away if you might have taken an excessive amount Coumadin.

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• Do not are drinking alcoholic beverages while you take Coumadin; it might raise the likelihood of Coumadin's unwanted effects.
• Do not change you activity level or weight without checking with your doctor; the likelihood of Coumadin's unwanted side effects could be increased.

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• Do not alter your eating routine without checking with your medical professional. Eat a normal, balanced diet. Foods that have high levels of vitamin K (eg, green vegetables, broccoli, liver, certain vegetable oils) may customize the effect of Coumadin. Ask a medical expert for the listing of foods which could affect Coumadin. Tell a medical expert if any foods out there really are a section of your diet plan.

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• Do not eat cranberry products or drink cranberry juice while you are taking Coumadin. Tell your medical professional if these items happen to be a part of your daily diet.
• Elevated body temperature may improve the effect of Coumadin. Be careful to avoid becoming overheated, especially during warm weather.
• Coumadin decreases blood clotting. Use caution while doing activities including brushing your teeth, flossing, or shaving. Avoid activities that will cause bruising or injury. Seek immediate medical assistance in the event you fall or injure yourself. Tell your medical professional for those who have unusual bruising or bleeding. Tell your medical professional in case you have dark, tarry, or bloody stools.

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• Do not take aspirin whilst you take Coumadin unless a medical expert tells you to. If you already take aspirin for any heart or another condition, talk with a medical expert about whether or not you should keep to go with Coumadin.

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• Tell your medical professional if you will likely be traveling or should you will likely be confined to a bed or chair for a long duration of time (eg, car or airplane ride). This may enhance your risk of developing a blood clot.

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• If therapy with Coumadin is stopped, the blood thinning effects takes 2 to 5 days after you stop taking it. Discuss any queries or concerns with a medical expert. Do not suddenly stop taking Coumadin without checking with your physician.

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• Lab tests, including certain blood clotting tests (eg, PT, INR), may be performed as you use Coumadin. These tests may be employed to monitor your problem or check for unwanted side effects. Be sure to keep all doctor and lab appointments.
• Use Coumadin with caution in Asian patients; they may be more responsive to its effects, especially bleeding.
• Use Coumadin with caution inside the elderly; they could be more understanding of its effects, especially bleeding.
• Coumadin ought to be used in combination with careful attention in kids; safety and effectiveness in youngsters have not been confirmed. Children might require more frequent diagnostic tests if they use Coumadin.
• If you could become pregnant, you need to work with an effective way of birth control while you take Coumadin. If you've got questions regarding effective birth control method, talk with your medical professional.

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• Pregnancy and breast-feeding: Do not use Coumadin if you are pregnant. It has been shown to harm the fetus. Avoid becoming pregnant whilst you consider it. If you think you could possibly be pregnant, contact your doctor immediately. It is not known if Coumadin can be found in breast milk. If you are or will likely be breast-feeding whilst you use Coumadin, check with your physician. Discuss any possible risks for your baby.

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