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Do NOT use Actoplus Met if:

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• should you possess a history of heart problems (eg, heart failure), abnormal liver function tests, lung or breathing problems, an under active thyroid, stomach or irregularity (eg, paralysis, blockage), adrenal or pituitary problems, eye or vision problems (eg, macular degeneration), bladder cancer, or lactic acidosis

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Some medicines may interact with Actoplus Met. Tell your health care provider if you're taking any other medicines, especially any of the following:

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• Calcium channel blockers (eg, nifedipine), corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control method pills), insulin, isoniazid, nicotinic acid, oral antidiabetics (eg, glipizide), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, albuterol, pseudoephedrine), or thyroid hormones (eg, levothyroxine) for the reason that probability of high or low blood glucose might be increased
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• Actoplus Met may cause dizziness. This effect may be worse in the event you take it with alcohol or certain medicines. Use Actoplus Met with caution. Do not drive or perform other possibly unsafe tasks before you discover how you reply to it.
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