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Uses

INDICATIONS

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Keppra is employed to deal with partial onset seizures in adults and children who're no less than 1 month old.
It is additionally used to help remedy tonic-clonic seizures in grown-ups and kids who're at least 6 years, and myoclonic seizures in older adults and kids who will be at the very least 12 years.

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INSTRUCTIONS

Take Keppra exactly as prescribed through your doctor. Do not take in larger or smaller amounts or for over recommended. Follow the directions on the prescription label.

Your doctor may occasionally alter your dose to ensure that you get the best results.

Keppra is usually taken twice daily. Take the medicine simultaneously daily. You may take Keppra with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not use a dose-measuring device, ask your friendly phamacist for just one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill could cause too much of the drug to be removed at once.

Use Keppra regularly to obtain the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using Keppra without first speaking with your medical professional, in case you feel great. You could have increased seizures should you stop by using this medicine suddenly. You ought to use less prior to deciding to stop the medication completely.

Seizures are often treated having a combination of different drugs. Use all medications as directed from your doctor. Read the medication guide or patient instructions given each medication. Do not improve your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card praoclaiming that you are taking Keppra. Any medical care provider who treats you need to know that you are taking seizure medication.

To make certain Keppra is not causing harmful effects, your kidney function ought to be tested. Visit your physician regularly.

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If you missed a dose - take the missed dose once you remember. Skip the missed dose if it's almost time for your upcoming scheduled dose. Do not take extra medicine to make up the missed dose.

DOSAGE

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Important Administration Instructions

Keppra is offered orally with or without food. The Keppra dosing regimen is dependent upon the indication, population, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with bodyweight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.

When using the oral solution in pediatric patients, dosing is weight-based (mg per kg) utilizing a calibrated measuring device (not just a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets should not be chewed or crushed.

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Pediatric Patients

Treatment needs to be initiated using a daily dose of 14 mg/kg by 50 % divided doses (7 mg/kg twice a day). The daily dose ought to be increased every fourteen days by increments of 14 mg/kg on the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the clinical study, the mean daily dose was 35 mg/kg in this age group. The effectiveness of lower doses hasn't been studied.

Treatment needs to be initiated which has a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two times a day). The daily dose should be increased into two weeks by an increment of 20 mg/kg for the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose could possibly be reduced. In the clinical study, the mean daily dose was 47 mg/kg within this generation.

Treatment needs to be initiated which has a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg two tmes a day). The daily dose must be increased every 2 weeks by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg two times a day). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose could possibly be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated having a daily dose of 500 mg given as twice daily dosing (250 mg twice daily). The daily dose should be increased every two weeks by increments of 500 mg to some maximum recommended daily dose of 1500 mg (750 mg two tmes a day).

For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment must be initiated using a daily dose of 1000 mg/day given as twice daily dosing (500 mg twice daily). The daily dose needs to be increased every fourteen days by increments of 1000 mg/day to a maximum recommended daily dose of 3000 mg (1500 mg twice a day).


Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were been shown to be effective. Although in some studies there were a propensity toward greater response with higher dose [see Clinical Studies], a regular surge in response with additional dose has not been shown.

Treatment must be initiated with a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments may be given (1000 mg/day additional every 14 days) to some maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day have been found in open-label studies for periods of a few months and longer. There is no evidence that doses in excess of 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment needs to be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage needs to be increased by 1000 mg/day every fourteen days on the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day will not be studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment needs to be initiated which has a dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Dosage must be increased by 1000 mg/day every two weeks for the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day hasn't been adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment should be initiated which has a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg twice daily). The daily dose ought to be increased every two weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). The effectiveness of doses lower than 60 mg/kg/day will not be adequately studied. Patients with body mass ≤ 20 kg needs to be dosed with oral solution. Patients with bodyweight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets must be administered.


Adult Patients With Impaired Renal Function
Keppra dosing must be individualized according to the patient's renal function status.

STORAGE

Store Keppra at room temperature from moisture, heat, and light-weight.

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Side Effects

Get emergency medical help in the event you have any of these signs and symptoms of a hypersensitivity to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to a medical expert, like: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at the same time should you possess a serious side-effect including:

Less serious Keppra side effects can sometimes include:

This just isn't a complete set of unwanted side effects while others may occur. Tell your physician about any unusual or bothersome unwanted effect.

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Precautions

You should not use Keppra in the event you are allergic to levetiracetam.

To make sure you can safely take Keppra, tell your medical professional in the event you have kidney disease or high blood pressure.

You may have thoughts about suicide while taking this medicine. Tell your medical professional in the event you have symptoms of depression or suicidal thoughts throughout the first a few months of treatment, or once your dose is changed.

Your family or any other caregivers should also be alert to changes with your mood or symptoms. Your doctor will need to check you at regular visits.

FDA pregnancy category C. It is just not known whether Keppra will harm an child, but using a seizure during pregnancy could harm the mother as well as the baby. Tell your physician in case you are pregnant or want to become pregnant while using this medication. Do not start or stop taking Keppra while pregnant without a medical expert's advice. Seizure control is very important when pregnant. The benefit of preventing seizures may outweigh any risks resulting from taking Keppra. Follow your doctor's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and could harm a nursing baby. You should not breast-feed if you are using Keppra. Do not give prescription drugs to your child devoid of the advice of your doctor. Your child's dose needs depend on age and weight. The child should remain underneath the care of a doctor while using this medicine.

Do not stop using Keppra without first conversing with a medical expert, even though you feel great. You could have increased seizures in the event you stop using Keppra suddenly. You may need to use much less before you decide to stop the medication completely.

You might have thoughts about suicide while taking Keppra. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your medical professional, such as: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card praoclaiming that you adopt Keppra. Any medical care provider who treats you should know that you're taking seizure medication.

Keppra may impair your notions or reactions. Be careful in the event you drive or do anything whatsoever that needs one to be alert. Tell a medical expert in case you are pregnant or intend to get pregnant while employing this medication. Do not start or stop taking Keppra when pregnant without your doctor's advice. Having a seizure during pregnancy could harm both mother and the baby. Seizure control is very important when pregnant and the great things about preventing seizures may outweigh any risks presented by using Keppra.

Avoid drinking alcohol. It can increase some of the unwanted effects of Keppra and may could also increase the potential risk of seizures. This medication may impair your notions or reactions. Be careful in the event you drive or do anything whatsoever that needs you to be alert.

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