See also Warning section.

This medication is used to take care of certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a medication that is psychiatricanti-psychotic type) that actually works by assisting to restore the balance of particular natural substances (neurotransmitters) within the brain.

Clozapine decreases hallucinations and aids in preventing suicide in people who tend to test to harm by themselves. It helps you to definitely clearly think more and definitely about yourself, feel less nervous, and take part in everyday life.

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If you are using the liquid form of this medication, read the Patient Suggestions Leaflet if available from your pharmacist before you start taking clozapine and any time you get a refill. When you have any relevant concerns, ask your doctor or pharmacist.

Simply take this medicine by mouth with or without food, as directed by your doctor. If you are taking the pills that dissolve in the lips, remove each tablet carefully from the blister pack immediately before taking your dose. Allow the tablets to dissolve on your tongue and swallow. You don't need to take the dissolving tablets with water. Discard any dissolving tablets that have been previously exposed to air due to packaging that is opened/damaged. Do not save your self them for your next dose.

If you use the liquid form of this medication, shake the bottle well for 10 seconds before each use. Carefully measure the dose using a special measuring device/spoon. Don't use a family group spoon because may very well not have the correct dose.

You should begin taking this drug at a low dose, increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Follow your doctor's instructions exactly. Your dosage is based on your condition that is medical and to therapy. Since clozapine can cause a decrease in white blood cells, you will have to get blood tests done regularly as directed. Be sure to keep all appointments of these laboratory tests. (See also Notes section.)

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You were on (see Missed Dose section) if you miss your doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose. Use this medication regularly in order to get the benefit that is most from this. To simply help you remember, use it at the time( that is same) each day.

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Do not stop taking clozapine without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Also, you might experience symptoms such as severe sweating, headache, sickness, vomiting, and diarrhoea. To prevent these symptoms while you might be stopping treatment with this drug, your doctor may reduce your dosage gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.

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It usually takes many weeks prior to the benefit that is full of drug takes effect. Inform your physician if your condition persists or worsens.

Part Effects

See also Warning section.

Drooling, drowsiness, dizziness, headache, shaking (tremor), vision problems (e.g., blurred vision), weight gain, and constipation may occur. Many of these effects (especially drowsiness) lessen as your body gets used to the medication. If any of these effects persist or worsen, contact your pharmacist or doctor quickly.

To stop constipation, keep a diet adequate in fiber, drink plenty of water, and workout. If you feel constipated while using the this medication, consult with your pharmacist for assistance in selecting a laxative (e.g., stimulant-type with stool softener).

Keep in mind that your doctor has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medicine may make your blood rarely sugar level rise, which can cause or worsen diabetes. Rarely, very conditions that are serious as diabetic coma may occur. Tell your physician right away if you develop symptoms of high blood sugar, such as increased thirst and urination. In the event that you already have diabetic issues, make sure to check always your bloodstream sugars regularly. Your medical professional may have to adjust your diabetes medication, exercise program, or diet.

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This medication could also cause weight that is significant and a rise in your cholesterol (or triglyceride) levels. These effects, along side diabetes, may increase your risk for developing heart infection. Discuss the dangers and advantages of treatment with your physician.

Tell your doctor right away if you have any serious side effects, including: facial/muscle twitching, seizures, uncontrollable motions.

Get help that is medical away if you have very serious part impacts, including: severe dizziness, fainting, mental/mood changes, trouble respiration with workout, sudden weakness, pain/redness/swelling of the arms/legs, persistent nausea/vomiting, stomach/abdominal pain, yellowing of eyes/skin.

This medication may hardly ever cause a tremendously serious condition called neuroleptic malignant syndrome (NMS). Get help that is medical away if you have associated with following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, change in the number of urine.

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A tremendously serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may add: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the United States -

Call your physician for medical advice about part results. You may report effects that are side Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You might report effects that are side Health Canada at 1-866-234-2345.


See also Warning and Side Effects sections.

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Before using clozapine, tell your physician or pharmacist in the event that you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which may cause allergies or other problems. Speak to your pharmacist for additional information.

Before using this medicine, tell your doctor or pharmacist your medical history, particularly of: history of blood disorders (such as for example leukemia, low white blood cell count), bowel problems (such as paralytic ileus, cranky bowel problem ), difficulty in breathing, diabetes/family history of diabetes, high cholesterol/triglyceride levels, glaucoma, heart problems, kidney problems, liver problems, obesity/family history of obesity, seizures, trouble urinating (such as prostate problems).

Clozapine may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as for example serious dizziness, fainting) that need medical attention appropriate away.

The risk of QT prolongation may be increased if you have particular conditions that are medical are taking other drugs that will impact the heart rhythm. Before using clozapine, tell your doctor or pharmacist of most the drugs you take and when you have some of the following conditions: certain heart issues (heart failure, slow heartbeat, QT prolongation within the EKG), genealogy of certain heart disease (QT prolongation in the EKG, unexpected cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Speak to your doctor about using clozapine safely.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit beverages that are alcoholic.

Tell your medical professional because you may be at a higher risk for a drop in your white blood cells if you are a descendent of Ashkenazi Jews.

Before having surgery, tell your doctor or dentist that you will be using this medicine.

Liquid services and products or tablets that are dissolving contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is encouraged if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your pharmacist or doctor about making use of this product safely.

Older grownups may be more sensitive to the relative part ramifications of this medication, specially constipation, dizziness, and QT prolongation (see above). Dizziness can boost the danger of falling.

During maternity, this medication should be used only when demonstrably needed. Babies born to moms who have used this drug over the last 3 months of maternity may rarely develop symptoms muscle that is including or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their first month, tell the doctor straight away.

Since untreated mental/mood issues (such as schizophrenia, schizoaffective disorders) can be a condition that is serious do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medicine may pass into breast milk and now have effects that are undesirable a nursing infant. Breast feeding is not recommended while taking clozapine. Consult your medical practitioner before breast-feeding.

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