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Mestinon (Pyridostigmine) affects chemicals in your body that are mixed up in the communication between nerve impulses and muscle movement.

Pyridostigmine is used to deal with the signs and symptoms of myasthenia gravis. It is also found in military personnel who have been exposed to nerve gas.

Pyridostigmine doubles for purposes unpublished in this medication guide.


Take the same manner prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your own prescription label.
Take this medicine with food or milk if it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill might cause excessive drug to be sold previously.

Measure liquid medicine having a special dose measuring spoon or medicine cup, not having a regular table spoon. If you do not possess a dose measuring device, ask the pharmacist for one.

The amount and timing of this medicine is extremely important towards the success of your respective treatment. Carefully follow your physician's instructions about how exactly much medicine to consider when to consider it.

Your doctor may occasionally make positive changes to dose to make sure you acquire the best results. You may be asked to keep a daily record of whenever you took each dose and just how long the effects lasted. This will help your medical professional determine if your dose needs to be adjusted.
If you need surgery, tell the surgeon in advance that you are using pyridostigmine. You may need to stop using the medicine for the limited time. Store at room temperature far from moisture and heat.


Take the medicine as prescribed by your doctor.


Keep the tablets of their original container, combined with canister of moisture-absorbing preservative that is included with this medicine.

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Active ingredient: Pyridostigmine

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Side Effects

Get emergency medical help in case you have these warning signs of a hypersensitive reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using pyridostigmine and call your physician immediately in case you have these serious unwanted side effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, anxiety attacks;

seizure (convulsions); or

worsening or no improvement with your signs and symptoms of myasthenia gravis.

Less serious unwanted side effects might include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This just isn't a complete listing of unwanted side effects yet others may occur. Call your medical professional for medical advice about unwanted side effects.

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You should avoid using pyridostigmine if you are allergic to it, or if you have a bladder or bowel obstruction.

To be sure you can safely take pyridostigmine, tell your doctor if you have these other concerns:


kidney disease;

an ulcer and other serious stomach disorder;

high hypertension, coronary disease;

overactive thyroid; or

a good seizures.

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It is not known whether pyridostigmine will harm an developing fetus. Tell your physician if you're pregnant or want to get pregnant while using prescription drugs. It just isn't known whether pyridostigmine passes into breast milk or when it could harm a nursing baby. Do not use this medication without telling a medical expert if you are breast-feeding a baby.

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Drugs interaction 

Tell your physician about all the medicines you have, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, yet others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications like darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators including ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that have an antihistamine such as diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication including quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;

irritable bowel medications like dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to help remedy Alzheimer's dementia, including donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid including betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list is not complete and other drugs may connect to pyridostigmine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your medical professional.

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