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Promethazine is in a small grouping of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals inside your brain. Promethazine also acts as a possible antihistamine. It blocks the effects with the natural chemical histamine in your body.

Promethazine is employed to deal with allergies such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine just isn't to use for treating signs and symptoms of asthma, pneumonia, and other lower respiratory tract infections.


Take promethazine just as prescribed through your doctor. Do not take it in larger amounts or over recommended. Follow the directions on your own prescription label.

Your doctor may occasionally improve your dose to ensure that you acquire the best is a result of medicines.

Promethazine could be taken with or without food or milk.

Measure liquid medicine using a marked measuring spoon or medicine cup, not having a regular table spoon. If you don't possess a dose-measuring device, ask your friendly phamacist first.

Call your physician if your symptoms tend not to improve, or if they deteriorate while taking promethazine.

This medication might cause one to have unusual results with certain medical tests. Tell any doctor who treats you that you will be using promethazine.

Seek emergency medical assistance if you think you might have used an excessive amount this medicine. Overdose symptoms can sometimes include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.

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Take becoming prescribed through your doctor.

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Side Effects

Get emergency medical help if you have any of these warning signs of a hypersensitivity: hives; lack of breath; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call your medical professional at the same time if you have these serious unwanted effects:

twitching, or uncontrollable movements of the eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might faint;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing with the skin or eyes);

urinating below usual or otherwise in any way;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy pores and skin; or

slow pulse rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine negative effects may include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing inside your ears;

weight gain, swelling in your hands or feet;

impotence, trouble having an orgasm; or


This is not a complete report on negative effects among others may occur. Tell your physician about any unusual or bothersome complication.

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Stop using promethazine and call a medical expert simultaneously if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early indications of dangerous unwanted side effects. Promethazine may cause side effects that may impair your opinions or reactions. Be careful in case you drive or do anything whatsoever that needs you to definitely be awake and alert. Avoid alcohol consumption, which may increase some of the unwanted side effects of promethazine. There are many other medicines that could communicate with promethazine. Tell your doctor about every one of the prescription and over-the-counter medications you have. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not use a new medication without telling your medical professional. Keep a list along of each of the medicines you have and show this list to your doctor or other doctor who treats you.

Important safety information:

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Promethazine mustn't be given to a kid younger than 24 months old. Promethazine can cause severe breathing problems or death in a kid younger than 2. Carefully follow your doctor's instructions when giving this medicine to a child of any age. Do not use this medication if you've got severe asthma, emphysema, and other breathing problem, or if you are allergic to promethazine or another phenothiazines like chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you might have certain conditions, you need a dose adjustment or special tests to securely use medicines. Before you take promethazine, tell a medical expert if you've got:

a good seizures;

heart disease or blood pressure;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or another breathing problem;

sleep apnea (breathing stops during sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulty with urination;

low degrees of calcium inside your blood (hypocalcemia); or

if you might have ever a serious side-effect while using the promethazine or other phenothiazine.

FDA pregnancy category C. It just isn't known whether promethazine is harmful for an developing fetus. Tell your physician in case you are pregnant or plan to conceive during treatment. It isn't known whether promethazine passes into breast milk or if it may harm a nursing baby. Do not use prescription drugs without telling your medical professional should you are breast-feeding your baby. Older adults could be very likely to have unwanted side effects from promethazine.

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