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Promethazine is several drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals within your brain. Promethazine also acts as an antihistamine. It blocks the effects from the naturally sourced chemical histamine in your body.

Promethazine can be used to treat hypersensitivity for example itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used being a sedative or sleep aid.

Promethazine is just not to be used in treating signs and symptoms of asthma, pneumonia, or other lower respiratory tract infections.


Take promethazine exactly as prescribed from your doctor. Do not take it in larger amounts and for more than recommended. Follow the directions in your prescription label.

Your doctor may occasionally change your dose to successfully acquire the best is a result of prescription drugs.

Promethazine may be taken with or without food or milk.

Measure liquid medicine using a marked measuring spoon or medicine cup, not using a regular table spoon. If you usually do not use a dose-measuring device, ask your pharmacist for starters.

Call your medical professional in case your symptoms tend not to improve, or if they get worse while taking promethazine.

This medication might cause you to definitely have unusual results with certain tests. Tell any doctor who treats you that you're using promethazine.

Seek emergency medical help if you think you have used too much of this medicine. Overdose symptoms might include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as prescribed through your doctor.


Store promethazine at room temperature away from moisture, heat, and lightweight.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you might have all of these warning signs of a hypersensitivity: hives; difficulty breathing; swelling of the face, lips, tongue, or throat. Stop using promethazine and call your physician at the same time if you might have these serious negative effects:

twitching, or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, issues with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might faint;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing with the skin or eyes);

urinating under usual you aren't at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy pores and skin; or

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine side effects may include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing inside your ears;

weight gain, swelling in your hands or feet;

impotence, trouble through an orgasm; or


This is not a complete listing of unwanted side effects and others may occur. Tell your medical professional about any unusual or bothersome unwanted effect.


Stop using promethazine and call your medical professional at once if you might have twitching or uncontrollable movements of your respective eyes, lips, tongue, face, arms, or legs. These could be early signs and symptoms of dangerous unwanted effects. Promethazine may cause unwanted side effects that could impair your notions or reactions. Be careful if you drive or do anything that will need one to be awake and alert. Avoid alcohol consumption, that may increase some from the negative effects of promethazine. There are many other medicines that can connect to promethazine. Tell a medical expert about all the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not employ a new medication without telling your physician. Keep a list together with you of each of the medicines you utilize and show this list to any doctor or any other physician who treats you.

Important safety information:

Promethazine really should not be directed at a child younger than 2 years old. Promethazine may cause severe breathing problems or death in a child younger than 2. Carefully follow your physician's instructions when giving this medicine to a kid of any age. Do not use medicines if you have severe asthma, emphysema, or another breathing problem, or should you are allergic to promethazine or other phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've certain conditions, you need a dose adjustment or special tests to soundly use this medication. Before you take promethazine, tell a medical expert if you've:

a good seizures;

heart disease or hypertension;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or other breathing problem;

sleep apnea (breathing stops while sleeping);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulty with urination;

low levels of calcium in your blood (hypocalcemia); or

if you might have ever had a serious side-effect while using the promethazine or other phenothiazine.

FDA pregnancy category C. It isn't known whether promethazine is harmful for an developing fetus. Tell your physician should you are pregnant or intend to conceive during treatment. It isn't known whether promethazine passes into breast milk or if it could harm a nursing baby. Do not use medicines without telling your medical professional in the event you are breast-feeding a child. Older adults may be prone to have negative effects from promethazine.

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