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Meldonium treats heart ischemia and its consequencesis.  It is found in treating brain circulation disorders. Meldonium is considered to improve Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was designed to enhance Athletic Training & Competitive Performance as well as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, with respect to the prescribed dose, is trusted for the treatment of different heart and vascular diseases, at the same time as for that improvement of labor capacity of healthy people at mental and physical overloads and during rehabilitation period.

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g daily
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, the therapy is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g two times a day before training. Duration of
treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) per day, utilizing the whole dose at once or dividing for just two takings. Course of treatment is 4-6 weeks.

• Cardialgia against the background of dyshormonal myocardiodystrophy – 500 mg each day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In procedure after elimination of acute disorders: 500 mg – 1 g every day, utilizing the whole dose at once or dividing it for two takings. In case of chronic disorders: 500 mg each day. General course of treatment is 4-6 weeks. Recurrent courses (usually 2-3 times per year) may be taken after consulting a health care provider.

• Diseases of peripheral arteries. 500 mg two times a day.

• Abstinence syndrome in case of chronic alcoholism. 500 mg 4x a day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.

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Please consult your physician ahead of employing this or some other vitamins and minerals or medications.

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Please consult a doctor regarding the required dosage.

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There isn't any data of cases of Meldonium overdosage. The drug is low-toxic.

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Keep far from direct sunlight.
Keep locked and faraway from children.
Store in dry place at room temperature.
Do not exceed storage temperature greater than 25 C

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Side Effects

Rarely - allergies (redness, rash, itching, oedema), at the same time as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Hypersensitivity, increased intracranial pressure (in violation in the venous outflow, intracranial tumors).


Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy haven't been determined.

Pregnancy and breast-feeding:

Not recommended during pregnancy (safety have not been proven). At the time of treatment should stop breastfeeding (known perhaps the breast milk gets).

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Interaction with other drugs and other kinds of interaction

The drug might be joined with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible continuing development of mild tachycardia and arterial hypotension, care needs to be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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