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Ponstel (Mefenamic Acid) is a small grouping of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Mefenamic acid works by reducing hormones that induce inflammation and pain in the body.

Mefenamic acid is used to deal with pain or inflammation caused by arthritis. It is also used to take care of menstrual pain.

Mefenamic acid doubles for other purposes unlisted with this medication guide.


Take prescription drugs just as it turned out prescribed for you personally. Do not take the medication in larger amounts, or take it for more than recommended by your doctor. Follow the directions on your prescription label.

If you're taking mefenamic acid for some time of your time, your doctor may want to check yourself consistantly to make certain prescription drugs just isn't causing harmful effects. Do not miss any scheduled visits to your physician.


Take the medicine as directed because of your doctor.

Seek emergency medical help if you believe you have accustomed to much of this medicine. Overdose symptoms might include nausea, vomiting, stomach pain, dizziness, drowsiness, black or bloody stools, paying blood, urinating lower than usual or otherwise in any respect, shallow breathing, fainting, or coma.


Store mefenamic acid at room temperature, from moisture, heat, and lightweight.


Active Ingredient: Mefenamic Acid



Side Effects

Get emergency medical help if you've got all of these signs and symptoms of an allergic reaction: hives; lack of breath; swelling of one's face, lips, tongue, or throat.

Stop taking mefenamic acid and seek medical help or call your medical professional simultaneously if you've got some of these serious negative effects:

chest pain, weakness, difficulty breathing, slurred speech, problems with vision or balance;

black, bloody, or tarry stools, paying out blood or vomit that appears like coffee grounds;

urinating lower than usual or otherwise in any respect;

pain, burning, or bleeding whenever you urinate;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects can include:

upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;

dizziness, headache, nervousness;

skin itching or rash;

dry mouth;

increased sweating, runny nose;

blurred vision; or

ringing inside your ears.

This just isn't a complete set of unwanted side effects and others may occur. Call your medical professional for medical advice about side effects.


This medicine can improve your probability of life-threatening heart or circulation problems, including heart attack or stroke. Do not use this medicine prior to or after having heart bypass surgery (also called cardio-arterial bypass graft, or CABG).

Seek emergency medical help if you have signs and symptoms of heart or circulation problems, such as chest pain, weakness, lack of breath, slurred speech, or difficulties with vision or balance.

This medicine can also increase your risk of serious effects for the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions may be fatal and gastrointestinal effects may appear without warning at any time while you are taking mefenamic acid. Older adults could possibly have a much better risk of these serious gastrointestinal unwanted side effects.

Call your physician at once if you've got symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or paying up blood or vomit that appears like coffee grounds.

Do not use any other over-the-counter cold, allergy, or pain medication without first asking your physician or pharmacist.

Do not drink alcohol while taking mefenamic acid. Alcohol can improve the risk of stomach bleeding.


Important safety information: 

Tell a medical expert should you be taking an antidepressant for example citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking some of these drugs with mefenamic acid could lead you to bruise or bleed easily.

Before taking mefenamic acid, tell your physician if you are taking any of these drugs:

a blood thinner for example warfarin (Coumadin);

a diuretic (water pill) like furosemide (Lasix);

cyclosporine (Gengraf, Neoral, Sandimmune);

lithium (Eskalith, Lithobid);

methotrexate (Rheumatrex, Trexall);

steroids (prednisone and others); or

aspirin or NSAIDs (non-steroidal anti-inflammatory drugs) for example diclofenac (Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), meclofenamate (Meclomen), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), yet others.

This list is not complete and there may be other drugs that may interact with mefenamic acid. Tell your physician about all the prescription and over-the-counter medications you have. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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