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Eldepryl is indicated as an adjunct within the control over Parkinsonian patients receiving care with levodopa/carbidopa who exhibit deterioration inside the quality of these response to this therapy.


Take this medicine only as directed from your doctor. Do not take a greater portion of it, do not take it more often, and don't take on it for a longer period than a medical expert ordered.

It is the most suitable to look at this medicine before breakfast and without liquids.

If you are with all the disintegrating tablet, make sure both hands are dry before you handle named. Do not open the blister pack made up of the tablet until you happen to be ready to go. Remove the tablet from the blister pack by peeling back the foil, then taking these days out. Do not push the tablet through the foil. Do not break or split today. Place the tablet about the top of your tongue, where it is going to melt quickly. Do not eat food or drink liquids for 5 minutes before or after taking this medicine.

If you miss a dose of this medicine, get it at the earliest opportunity. However, whether it is almost time for your forthcoming dose, skip the missed dose and go back to your normal dosing schedule. Do not double doses.


The dose of the medicine vary for various patients. Follow your physician's orders or the directions around the label. The following information includes just the average doses of the medicine. If your dose differs from the others, tend not to change it unless your physician informs you to take action.

The amount of medicine that you just take depends around the strength with the medicine. Also, the volume of doses you adopt daily, some time allowed between doses, and also the amount of time you adopt the medicine depend on the problem for which you happen to be while using medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in the closed container at room temperature, faraway from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of youngsters.
Do not keep outdated medicine or medicine no longer needed.


Eldepryl is a levorotatory acetylenic derivative of phenethylamine. It is commonly referred to inside the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along with its needed effects, a medicine could cause some unwanted effects. Although not most of these negative effects may occur, when they occur they might need medical assistance.

Check with your physician immediately if any of the following unwanted effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements with the body
increased sensitivity in the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood and other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly when getting up from your lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling things that are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling in the hands, feet, or lips
puffing of the cheeks
rapid or worm-like movements in the tongue
restlessness or wish to keep moving
severe stomach pain
shakiness in the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation in the mouth
tightness within the chest
trembling or shaking with the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements in the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material seems like coffee grounds

Get emergency help immediately if any of these the signs of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure levels
severe spasm where the head and heels are bent backward and also the body arched forward
troubled breathing

Some negative effects may occur that always do not need medical help. These side effects might go away during treatment since your body adjusts towards the medicine. Also, your overall health care professional just might tell you about approaches to prevent or reduce some unwanted effects. Check with your health care professional if any of these negative effects continue or are bothersome or if you might have any questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning from the lips, mouth, or throat
dryness or soreness in the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing in the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing from the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other unwanted side effects not listed can also occur in some patients. If you notice some other effects, check using your medical practioner.


It is very important that your physician look at the progress at regular visits to allow for changes in your dose also to pay attention to any uncomfortable side effects.

Do not take selegiline if you have used meperidine (e.g., Demerol®) or an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 14 days. If you do, you could develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body temperature, elevated blood pressure levels, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you happen to be applying this medicine. Using these medicines together can cause uncomfortable side effects.

Selegiline could cause serious negative effects when used along with some antidepressants. Tell your physician if you've got used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past fourteen days.

When selegiline is taken at doses of 10 mg or less per day to the management of Parkinson's disease, there are no restrictions on food or beverages consume or drink. However, the chance exists that dangerous reactions, for example sudden high hypertension, may occur if doses higher than those employed for Parkinson's disease are taken with foods, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for about two weeks once you stop investing in this medicine, due to the fact, beverages, as well as other medicines may continue to react with selegiline when it was taken in doses greater than those usually useful for Parkinson's disease.

Check with a medical expert or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you're using this medicine. These may be signs of a serious complication that will possess a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, specially when you will get up coming from a lying or sitting position. Getting up slowly might help. If the problem continues or gets worse, seek advice from your doctor.

Selegiline could cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt items of ice in your mouth, or make use of a saliva substitute. However, in case your mouth is constantly feel dry in excess of fourteen days, check with your medical doctor or dentist. Continuing dryness with the mouth may increase the possibility of dental disease, including oral cavaties, gum disease, and fungus infections.

It is essential that your doctor look at the skin for melanoma (tumor) regularly if you've Parkinson's disease.

Do not stop investing in this medicine without first checking with your medical professional. Your doctor might prefer that you reduce gradually the amount you're taking before stopping completely.

Hallucinations may appear in some patients. This is more common with elderly patients. If you might have hallucinations, check with your doctor.

Some individuals who have used this medicine had unusual alterations in their behavior. Talk with your physician should you start having issues with gambling or increased sex drive while applying this medicine.

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