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Micronase (Glyburide) is surely an oral diabetes medicine which enables control blood sugar levels.

Glyburide is utilized to deal with diabetes type 2 symptoms.

This medicine is not for treating type 1 diabetes.

Glyburide doubles for other purposes unlisted with this medication guide.


Take the same manner prescribed from your doctor. Do not take in larger or smaller amounts and for longer than recommended. Follow the directions on the prescription label. Your doctor may occasionally improve your dose to successfully get the best results.

Take glyburide with your first meal during the day, unless a medical expert informs you otherwise.

Your blood glucose levels should be checked often, and you will need other blood tests at your doctor's office. Visit a medical expert regularly.
Know the warning signs of low blood glucose levels (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar for sale in case you've got symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, readily injection of glucagon. Your doctor can present you with a prescription for a glucagon emergency injection kit and let you know the way to give the injection.

Also watch for signs and symptoms of blood glucose that is certainly too much (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dermititis, blurred vision, and weight reduction.

Check your blood glucose carefully after a period of stress or illness, in case you travel, exercise more than usual, are drinking alcoholic beverages, or skip meals. These things may affect your glucose levels and your dose needs can also change.

Your doctor may want one to stop taking glyburide to get a short time in the event you get ill, have a fever or infection, or if you might have surgical treatment or a medical emergency.
Ask your doctor the best way to adjust your glyburide dose as needed. Do not make positive changes to medication dose or schedule without your medical professional's advice.

If you'll find any adjustments to the brand, strength, or kind of glyburide you employ, your dosage needs may change. Always check your refills to make sure you have received the correct brand and kind of medicine prescribed through your doctor.


Take as prescribed because of your doctor.


Store at room temperature, protected against moisture, heat, and lightweight.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and have emergency medical help if you might have some of these signs of an allergic reaction: hives; lack of breath; swelling of your face, lips, tongue, or throat. Stop taking medicines and call your medical professional immediately if you've some of these serious unwanted effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of the epidermis or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots under your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious negative effects may include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete list of unwanted side effects yet others may occur. Call your medical professional for health advice about negative effects.


You should avoid using medicines in case you are allergic to glyburide, or:

in the event you are receiving care with bosentan (Tracleer);

if you've type 1 diabetes; or

in the event you are in a state of diabetic ketoacidosis (call a medical expert for treatment with insulin).

To be sure to can safely take glyburide, tell your doctor if you have any of these other conditions:

hemolytic anemia (a lack of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

in case you are allergic to sulfa drugs; or

if you've got been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may enhance your risk of serious heart disease. However, not treating your diabetes damages your heart as well as other organs. Talk to a medical expert regarding the risks and advantages of treating your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an child. Similar diabetes medications have caused severe hypoglycemia in infants whose mothers had used the medication close to the period of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using the medicines. It is not known whether glyburide passes into breast milk or if it could possibly harm a nursing baby.

Do not use medicines without telling your medical professional should you are breast-feeding an infant. Older adults could be very likely to have low blood glucose while taking glyburide.


Important safety information:

You should not use prescription drugs in case you are allergic to glyburide, if you are receiving treatment with bosentan (Tracleer), if you've got type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Before taking glyburide, tell your physician in case you are allergic to sulfa drugs, if you've been using insulin or chlorpropamide (Diabinese), or if you might have hemolytic anemia (too little red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to never let your blood sugar levels get too low. Low blood glucose (hypoglycemia) can happen in case you skip dinner, exercise to much time, are drinking alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your household and good friends know the way to assist you in a crisis.

Drug interactions

Tell your doctor about all the other medications you utilize, especially:

a blood thinner like warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), while others; or

an antibiotic including ciprofloxacin (Cipro), levofloxacin (Levaquin), yet others.

Using certain medicines will make it tougher for that you tell when you might have low blood sugar. Tell a medical expert if you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers including atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), while others.

You could possibly be more likely to have hyperglycemia (high blood glucose levels) in case you take glyburide with:


diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine while others);

thyroid medicine (Synthroid while others);

birth control pills and also other hormones;

heart or blood pressure medications (Cartia, Cardizem, Nifedical, Covera, Verelan, among others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, among others);

seizure medicines (Dilantin among others); and

diet pills or medicines to help remedy asthma, colds or allergies.

You could possibly be prone to have hypoglycemia (low blood glucose) if you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, yet others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are not complete and you can find many other medicines that may increase or minimizing the effects of glyburide on lowering your blood glucose levels. Tell your doctor about all medications you employ. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling a medical expert.


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